病毒多重感染对呼吸道合胞病毒毛细支气管炎严重度的影响  

Effects of virus coinfection on the severity of respiratory syncytial virus bronehiolitis

作　　者：姚欢银[1] 张佩红[1] 章杭湖[1] 李华浚[1] 刘淑梅[1] 陈啸洪[1] 

机构地区：[1]绍兴市人民医院浙江大学绍兴医院儿科,浙江省绍兴312000

出　　处：《中国基层医药》2015年第17期2586-2588,共3页Chinese Journal of Primary Medicine and Pharmacy

基　　金：浙江省医药卫生一般研究计划（2015KYA219）

摘　　要：目的：通过对286例呼吸道合胞病毒（RSV）毛细支气管炎患儿临床分析，探讨病毒多重感染对其严重度的影响。方法对286例RSV毛细支气管炎进行多种病毒抗体检测，观察病毒多重感染对不同程度的RSV毛细支气管炎的影响。结果 RSV毛细支气管炎合并感染的比例达29．37％，以双重感染为主；与单纯RSV感染相比，合并感染患儿重症病例明显增多（χ2＝128．7，P＜0．01）。结论 RSV毛细支气管炎合并其他呼吸道病毒感染并不少见，病毒多重感染可以加重疾病的严重程度。Objective To investigate the effects of virus coinfection on the severity of respiratory syncytial virus（RSV）bronchiolitis through the clinical analysis of 286 cases.Methods Various virus antibody were measured by using ELISA in 286 cases of RSV bronchiolitis.The frequency of respiratory virus coinfection on the severity of RSV bronchiolitis was observed.Results RSV bronchiolitis complicated with virus coinfection ratio reached 29.37%,especially with the double infection.Compared to patients with RSV infection,the severe cases increased sig-nificantly in patients with virus coinfection（χ2 =128.7,P〈0.01）.Conclusion Other respiratory viruses coinfection are not uncommon in infants with RSV bronchiolitis and may increase the severity of RSV bronchiolitis.

关 键 词：呼吸道合胞病毒 儿童 细支气管炎 病毒 细菌 

分 类 号：R725.6[医药卫生—儿科]