3D-UTE评价腰椎间盘软骨终板缺损与椎间盘退变的相关性  

Study of correlation between cartilaginous endplate defects and intervertebral disc degeneration of lumbar spine with MR 3D-UTE technique

作　　者：蒋小莉[1] 査云飞[1] 王娇[1] 邢栋[1] 刘昌盛[1] 邱丽[1] 

机构地区：[1]武汉大学人民医院放射科,武汉430060

出　　处：《放射学实践》2015年第9期952-955,共4页Radiologic Practice

基　　金：湖北省自然科学基金资助项目(2013CFB242);湖北省卫生厅科研资助项目(JX6B68)

摘　　要：目的:采用磁共振超短回波成像(3D-UTE)技术评价腰椎软骨终板缺损与腰椎间盘退变的相关性。方法:本研究共招募志愿者50例,共扫描腰椎椎间盘250个,腰椎软骨终板500个。受检者行常规腰椎MRI检查评价椎间盘Pfirrmann分级,以3D-UTE序列显示腰椎间盘终板软骨完整性。按照有无邻近软骨终板缺损将腰椎间盘分为4组,分别为无邻近终板软骨缺损组(A组)、只有头侧终板软骨缺损组(B组)、只有尾侧终板软骨缺损组(C组)及头尾侧终板软骨皆缺损组(D组)。评价软骨终板完整性与椎间盘Pfirrmann分级的相关性。结果:A组有椎间盘53个,其中PfirrmannⅠ级49个,Ⅱ级4个;B组有椎间盘62个,其中PfirrmannⅠ级6个,Ⅱ级55个,Ⅲ级1个;C组有椎间盘70个,其中PfirrmannⅠ级6个,Ⅱ级63个,Ⅲ级1个;D组有椎间盘65个,其中PfirrmannⅡ级39个,Ⅲ级26个。Kendall等级相关检验显示椎间盘终板软骨缺损程度越严重,腰椎间盘退变程度越重(H=0.67,P<0.01)。结论:3D-UTE可以显示腰椎间盘软骨终板的完整性,椎间盘终板软骨缺损与腰椎间盘退变程度密切相关。Objective：To evaluate the correlation between cartilaginous endplate （CEP）defects and inter-vertebral disc degeneration of lumbar spine with MR 3D-UTE technique.Methods：50 healthy volunteers were recruited.Conventional MRI was performed,totally 250 inter-vertebral discs and 500 CEP of lumbar spine were scanned.Pfirrmann classification was used to evaluate the inter-vertebral disc.MR 3D-Ultrashort echo time （3D-UTE）technique was used to display the in-tegrity of CEP.According to whether CEP defect was existed,there were：Group A：no CEP defect was existed;Group B：only cranial CEP defect;existed;Group C：only caudal CEP defect existed;and Group D：both cranial and caudal CEP defects were presented.The correlation between CEP integrity and the Pfirrmann classification of inter-vertebral disc degeneration was evaluated with the Kendall rank correlation test.Results：In this study,there were Group A,53 discs （PfirrmannⅠ,n=49;Pfirrmann Ⅱ,n=4）;Group B,62 discs （PfirrmannⅠ,n=6;Pfirrmann Ⅱ,n=55;Pfirrmann Ⅲ,n=1 ）;Group C,70 discs （PfirrmannⅠ,n=6;Pfirrmann Ⅱ,n=63;Pfirrmann Ⅲ,n=1 ）and Group D,65 discs （Pfirrmann Ⅱ,n=39;Pfir-rmann Ⅲ,n=26）.The Kendall rank correlation test showed that the more serious the degree of CEP defect,the more severe the lumbar disc degeneration （H=0.67,P ＆lt;0.01）.Conclusion：The integrity of CEP could be displayed on MR 3D-UTE se-quence,the CEP defect was highly associated with inter-vertebral disc degeneration of lumbar spine.

关 键 词：软骨终板 腰椎间盘退行性变 磁共振成像 

分 类 号：R681.53[医药卫生—骨科学]