非典型病原体感染在社区呼吸道感染中的地位  

The status of atypical pathogens in the community respiratory tract infection

作　　者：费爱华[1] 陈怡[2] 

机构地区：[1]上海交通大学医学院附属新华医院急诊科,上海200092 [2]上海交通大学医学院附属仁济医院急诊科

出　　处：《中国急救医学》2015年第9期776-779,共4页Chinese Journal of Critical Care Medicine

摘　　要：目的探讨非典型病原体感染在社区呼吸道感染中的地位，指导临床合理用药。方法分析非典型病原体感染发病率、并发症及病死率，结合致病机制，探讨各类并发症及耐药对疾病治疗的影响。结果非典型病原体是我国社区呼吸道感染的主要病原体，易引起多种疾病并发症，加重患者预后。病原体对大环内酯类药物耐药，使用氟喹诺酮类药物治疗效果更好。结论非典型病原体感染在社区呼吸道感染中占有重要地位，初始经验治疗时覆盖非典型病原体可改善患者预后，显著缩短患者住院时间、降低死亡率。Objective To investigate the status of atypical pathogens in the community respiratory tract infection for guiding clinical rational drug use. Methods We analyzed the incidence ofatypical pathogens, incidence of complications and mortality rate. Incorporationed with pathogenic mechanism, to investigate the influence of complications and drug resistance on disease treatment. Results Atypical pathogens was the main pathogenesis of community - acquired pneumonia in our country, patients with atypical pathogens respiratory tract infection had a poor prognosis and were valuable to multiple complication. Patients with fluoroquinolone treatment had a better treatment effect compared with macrolide due to macrolide resistance. Conclusion Atypical pathogens played a important role in the community respiratory tract infection. The initial empirical treatment can significantly improve the prognosis of patients with atypical pathogens, reduce days of stay in hospital and mortality rates.

关 键 词：非典型病原体 呼吸道感染 经验性治疗 

分 类 号：R563.1[医药卫生—呼吸系统]