高血压合并代谢综合征与颈动脉粥样硬化相关性分析  

Association between carotid atherosclerosis and hypertension with metabolic syndrome

作　　者：宋宇新[1] 

机构地区：[1]江苏启东市中医院,江苏启东226200

出　　处：《中国医学工程》2015年第8期13-14,共2页China Medical Engineering

摘　　要：目的探讨高血压合并代谢综合征与颈动脉粥样硬化的相关性。方法选择高血合并代谢综合征患者32例,单纯高血压病患者30例。全部患者均进行颈动脉血管超声检查,并收集资料,比较两组颈动脉粥样硬化发生情况。结果观察组与对照组相比较,体重指数(BMI)、空腹血糖(FPG)、餐后2 h血糖(2 h PG)、胰岛素抵抗指数(HOMA-IR)、血清总胆固醇(TC)、三酰甘油(TG)水平均显著升高(P<0.05)。颈总动脉及颈内动脉内中膜厚度明显增厚(P<0.05);观察组颈总动脉粥样硬化发生率为81.2%,高于对照组60.0%(P<0.05);颈总动脉左右侧血管内径及阻力指数均明显高于对照组。结论高血压合并代谢综合征患者更易发生颈动脉粥样硬化,代谢综合征可促进高血压患者颈动脉粥样硬化的形成。【Objective】To investigate the association between carotid atherosclerosis and hypertension with metabolic syndrome. 【Methods】32 patients with hypertension complicating the metabolic syndrome and 30 hypertension patients were for control group. Carotid intina media thickness（IMT） was measured by ultrasonic. And Body mass index（BMI）. Fasting plama glucose（FPG）. 2hours PG, homeostasis model assessment for insulin resistance（HOMA-IR） and plasma TC. TG. LDL-C. HDL-C were measured.【Results】BMI,FPG,2 h PG,HOMA-IR,TC,TG were increased in observation group than in controls.Carotid artery and carotid artery intima-media thickness significantly increased（P〈0.05）.Observation group carotid atherosclerosis incidence rate was 81.2%, higher than that of the control group（60.0%）（P〈0.05）.Carotid artery or lateral vessel diameter and resistance index were significantly higher than those of the control group.【Conclusion】Hypertension with metabolic syndrome could easily result to artery atherosclerosis, metabolic syndrome may course more severe carotid atherosclerosis.

关 键 词：高血压 代谢综合征 颈动脉粥样硬化 

分 类 号：R544.1[医药卫生—心血管疾病]