外科手术结合注射用鼠神经生长因子治疗胸腰段脊髓损伤的临床应用  

Surgical Operation Combined with the Application of Growth Factors in the Treatment of Thoracolumbar Spinal Cord Injury in Rats by Injection of Nerve

作　　者：赵冰[1] 黄玉国[1] 卢占斌[1] 徐丽[1] 张军军[1] 王立功[1] 

机构地区：[1]河北省唐山市第二医院脊柱三科,唐山063000

出　　处：《中国医药导刊》2015年第8期832-834,共3页Chinese Journal of Medicinal Guide

摘　　要：目的:探讨外科手术联合鼠神经生长因子对治疗胸腰段外伤合并脊髓损伤患者的临床疗效。方法:对我院58例胸腰椎外伤合并脊髓损伤患者的临床资料进行分析,分为治疗组30例和对照组28例,两组病例均为胸腰段骨折合并脊髓损伤患者,均采用脊柱后路复位椎板切除减压植骨椎弓根螺钉内固定手术常规治疗,治疗组术后加用注射用鼠神经生长因子,疗程为4周~3个月,对两组治疗后患者的脊髓功能恢复程度进行评价。结果:所有患者术后切口一期愈合,随访时间6~24个月,并通过ADL评分系统进行比较,治疗组患者的脊髓功能恢复程度明显优于对照组,差异有统计学意义。结论:鼠神经生长因子可作为胸腰段脊髓损伤术后常规治疗方案,对神经功能恢复有显著作用。Objective： To evaluated the clinical efficacy of surgical operation combined with nerve growth factor on rats for thoracolumbar spinal cord injury patients.Methods： The clinical data of our hospital in 58 cases thoracolumbar trauma complicated with spinal cord injury patients analysis,divided into treatment group（30 cases） and control group（28 cases）,all of two groups of cases thoracolumbar fractures combined with spinal cord injury patients,using posterior spinal lamina reduction decompression bone graft and pedicle screw internal fixation for the treatment of conventional treatment,by injection of mouse nerve growth factor was added in the treatment group,treatment for 4 weeks^3 months,evaluation of treatment in the two groups after the spinal cord function degree of recovery.Results： All the patients after healing of the incision,follow-up 6~24 months and the ADL scoring system were compared,treatment group,the recovery of spinal cord function was significantly better than the control group,the difference was statistically significant.Conclusion： Mouse nerve growth factor can be as thoracolumbar spinal cord injury patients after conventional treatment,on nerve function recovery had a significant effect.

关 键 词：鼠神经生长因子 脊髓损伤 胸腰段 

分 类 号：R687.3[医药卫生—骨科学]