急性心肌梗死恢复期新发房颤的发生率与危险因素  

Risk factors of new-onset atrial fibrillation during recovery period of acute myocardial infarction

作　　者：汪沁沁[1] 叶晨阳 任雨笙[1] 樊民[1] 吴宗贵[1] 

机构地区：[1]第二军医大学长征医院心血管内科,上海200003 [2]北京307医院消化肿瘤科,北京100071

出　　处：《心脏杂志》2015年第5期585-587,共3页Chinese Heart Journal

摘　　要：目的分析急性心肌梗死（AMI）患者恢复期（心肌梗死28d后）出现新发房颤的发生率与危险因素。方法回顾性分析2009年6月-2011年6月全部212例因AMI入住长征医院治疗且无房颤病史的患者一般情况，相关检查结果，以及心肌梗死1年内后续治疗、转归情况，并对可能影响患者恢复期新发房颤的因素进行logistic回归模型分析。结果多因素logistic回归分析表明，高龄（P〈0．05，OR=5．61），高血压病（P〈0．05，OR=5．89），左心室射血分数（LVEF）降低（P〈0．01，OR=6．3），未行急诊经皮冠状动脉介入（PCI）术（P〈0．01，OR=6．01），糖尿病（P〈0．05，OR=3．59）以及出院后无法耐受B受体阻滞剂治疗（P〈0．01，OR=6．1）等是新发房颤的危险因素。结论AMI患者恢复期出现新发房颤的危险因素为高龄，高血压病，LVEF降低，未行急诊PCI术，糖尿病以及出院后无法耐受B受体阻滞剂治疗。AIM To explore the risk factors of new onset atrial fibrillation （AF） during the recovery period （ 〉28 days） of acute myocardial infarction （AMI）. METHODS Clinical data of 212 AMI patients during 1 year after admission were retrospectively analyzed, including the general conditions, test results, treatment and follow-up data. Patients were admitted to hospital for AMI from June 2009 to June 2011. Logistic regression analysis was conducted to analyze the risk factors of new-onset AF after hospital discharge. RESULTS Logistic regression analysis showed that age 〉 75 years （P 〈 0. 05, OR = 5.61 ）, hypertension （P 〈 0. 05, OR = 5.89）, LVEF 〈 50% （P 〈 0. 01, OR = 6. 3 ）, non-emergency PCI （P 〈 O. 01, OR = 6. O1 ）, diabetes mellitus （P 〈 0. 05, OR = 3.59） and B-blocker intolerance （P 〈 0. 01, OR = 6. 1 ） were associated with an increased risk of new-onset AF during the recovery period of myocardial infarction. CONCLUSION Age 〉 75 years, hypertension, LVEF 〈 50%, non-emergency PCI, diabetes mellitus and B-blocker intolerance are risk factors for new-onset AF during the recovery period of AMI.

关 键 词：心肌梗死 急性 房颤 危险因素 LOGISTIC回归模型 

分 类 号：R541.4[医药卫生—心血管疾病]