炎症血栓状态在心血管疾病的研究进展  

Progress of thromboinflammatory state in cardiovascular diseases

作　　者：屈会娟[1] 李东泽[1] 杨毅宁[1] 

机构地区：[1]新疆医科大学第一附属医院心脏中心,新疆乌鲁木齐830054

出　　处：《心脏杂志》2015年第5期613-616,共4页Chinese Heart Journal

基　　金：国家自然科学基金项目资助(81060025);教育部新世纪优秀人才支撑计划项目资助(NCET-11-1074)

摘　　要：最近研究发现许多疾病是以炎症血栓状态为特点的,血液中的血细胞与血管壁的相互作用是血栓形成和炎症反应的途径。针对这些途径的措施可能有利于炎症性疾病和心血管疾病治疗。本文从分子和细胞间相互作用机制总结了炎症和血栓与心血管疾病的联系。Recent research has found that several disease conditions are characterized by a thromboinflammatory state in which interactions of blood cells and components with the vascular wall perpetuate both thrombotic and inflammatory pathways. Targeting these pathways may be of benefit in inflammatory conditions and cardiovascular diseases. Ongoing clinical trials should provide insight into the hypothesis that the thromboinflammatory state contributes to adverse clinical outcomes. This article summarizes the molecular and cellular links between inflammation and thrombosis in the context of cardiovascular and other thromboinflammatory diseases.

关 键 词：心血管疾病 炎症 血栓 

分 类 号：R54[医药卫生—心血管疾病]