Histopathology and Ultrastructural Pathology of Cyprinid Herpesvirus Ⅱ(CyHV-2) Infection in Gibel Carp, Carassius auratus gibelio  

作　　者：JIANG Nan XU Jin MA Jie FAN Yuding ZHOU Yong LIU Wenzhi ZENG Lingbing 

机构地区：[1]Division of Fish Disease, Yangtze River Fisheries Research Institute, Chinese Academy of Fishery Sciences [2]College of Fisheries, Huazhong Agricultural University

出　　处：《Wuhan University Journal of Natural Sciences》2015年第5期413-420,共8页武汉大学学报（自然科学英文版）

基　　金：Supported by the Earmarked Fund for China Agriculture Research System(CARS-46-11);the Special Scientific Research Funds for Central Non-profit Institute,Chinese Academy of Fishery Sciences(2014A06XY07);the Wuhan Science and Technology Plan Grant,Hubei Province(2014020202010138)

摘　　要：Cyprinid herpesvirus II （CyHV-2） infection is identi- fied in cultured gibel carp, Carassius auratus gibelio, with high mortality in China in recent years. Histological pathology includes acute hepatocellular necrosis, splenic necrosis, kidney necrosis, hyperplasia of the secondary lamellae with focal necrosis. Acute necrotic myocarditis and granulocytes are prominent within the cardiac lumen in infected fish. In addition, necrosis is observed in the submucosa and mucosa epithelium of intestinal tract. Edemas are observed in renal glomerulus, submucosa and mucosa epithe- lium of intestinal tract, myocardial cells and neurons. Transmis- sion electron microscopy indicates the cytoplasmic inclusions in splenocytes, glomerulus cells and hematopoietic tissue cells of kidney, epithelial cells of gills and brain cells. The histopathology and ultrastructural pathology in CyHV-2 infected gibel carp are characterized with extensive necrosis and cytoplasmic inclusions in spleen, kidney, gill and brain, which suggests that CyHV-2 may mainly infect the spleen, kidney, gill and brain of fish.Cyprinid herpesvirus II （CyHV-2） infection is identi- fied in cultured gibel carp, Carassius auratus gibelio, with high mortality in China in recent years. Histological pathology includes acute hepatocellular necrosis, splenic necrosis, kidney necrosis, hyperplasia of the secondary lamellae with focal necrosis. Acute necrotic myocarditis and granulocytes are prominent within the cardiac lumen in infected fish. In addition, necrosis is observed in the submucosa and mucosa epithelium of intestinal tract. Edemas are observed in renal glomerulus, submucosa and mucosa epithe- lium of intestinal tract, myocardial cells and neurons. Transmis- sion electron microscopy indicates the cytoplasmic inclusions in splenocytes, glomerulus cells and hematopoietic tissue cells of kidney, epithelial cells of gills and brain cells. The histopathology and ultrastructural pathology in CyHV-2 infected gibel carp are characterized with extensive necrosis and cytoplasmic inclusions in spleen, kidney, gill and brain, which suggests that CyHV-2 may mainly infect the spleen, kidney, gill and brain of fish.

关 键 词：Cyprinid herpesvirus II gibel carp HISTOPATHOLOGY ultrastructural pathology NECROSIS 

分 类 号：S965.117[农业科学—水产养殖] S435.121.4[农业科学—水产科学]