痔上黏膜环切钉合术致术后近期控便功能异常的临床病理特征总结  

Correlation between shortterm anal control function and number of pacinian corpuscles in patients undergoing procedure for prolapse and hemorrhoids or Milligan-Morgan hemorrhoidectomy

作　　者：颜帅[1] 刘翔[2] 钱海华[3] 杨会举[2] 曾笛 刘佃温[2] 

机构地区：[1]苏州市中医医院肛肠科,江苏省苏州市215009 [2]河南中医学院第三附属医院肛肠科,河南省郑州市450000 [3]南京中医药大学附属医院肛肠科,江苏省南京市210023 [4]郑州市第七人民医院肛肠科,河南省郑州市450000

出　　处：《世界华人消化杂志》2015年第24期3967-3972,共6页World Chinese Journal of Digestology

摘　　要：目的:比较痔上黏膜环切钉合术(procedure for prolapse and hemorrhoids,PPH)和传统痔切扎术(Milligan-Morgan)临床术后近、远期控便功能与切除组织病理组织中的环层小体之间的相关性.方法:搜集苏州市中医医院肛肠科、江苏省中医院肛肠科和河南中医学院第三附属医院2013-06/2014-06行传统痔切扎术和PPH术的90例患者的临床资料,每组各45例,所有患者切除组织均行阿利新蓝、核固红染色,分析切除组织中环层小体数量的差异,与临床观察指标比较有无统计学意义.结果:两组近期控便自制功能比较有统计学差异(P<0.05),两组切除组织中环层小体计数有差异;与传统痔切扎术组相比,PPH术组环层小体数目明显升高(42.7个±9.86个vs 11.3个±6.11个),统计学具有显著性差异(P<0.05).环层小体数目与近期肛门自制功能评分呈正相关.结论:PPH手术与传统痔切扎术组相比远期控便能力无明显差异.PPH术组环层小体计数高于传统痔切扎术组,这可能是PPH术组手术近期肛门控便功能劣于传统痔切扎术组的原因.AIM：To analyze the relevance between pathological damage and clinical complications of Milligan-Morgan hemorrhoidectomy and procedure for prolapse and hemorrhoids（PPH）.METHODS：Clinical data for 90 patients who were operated at Suzhou Hospital of Traditional Chinese Medicine,the Third Affiliated Hospital of He＇nan College of Traditional Chinese Medicine and Affiliated Hospital of Nanjing University of TCM from June 2013 to June2014 were retrospectively.The patients were divided into two groups,patients undergoing Milligan-Morgan hemorrhoidectomy and those undergoing PPH.Anal control function was assessed in both groups.All of surgical specimens underwent Alcian blue staining to count the number of pacinian corpuscles.Then the relevance between the pathological damage and clinical complications was analyzed.RESULTS：The short-term anal control function had no statistically significant difference between the two groups.The number of pacinian corpuscles in resected tissue differed significantly between the PPH and MilliganMorgan groups（P 〈0.05）.Compared with the Milligan-Morgan group,the number of pacinian corpuscles significantly increased in the PPH group（11.3 ± 6.11 vs 42.7 ± 9.86,P 〈0.05）.There was a positive correlation between anal control function and the number of Pacinian corpuscles.CONCLUSION：The short-term anal control function had a significant difference between patients undergoing PPH and those undergoing traditional hemorrhoid surgery.The number of pacinian corpuscles was significantly higher in the PPH group than in the traditional hemorrhoid surgery group,which may be the reason why the short-term anal control function in the PPH group was inferior to that of the traditional hemorrhoid surgery group.

关 键 词：痔上黏膜环切钉合术 病理 环层小体 

分 类 号：R657.1[医药卫生—外科学]