浙江省盐碘含量调整后人群碘营养水平及甲状腺病情分析  

Iodine nutritional status and goiter after adjustment of salt iodine concentration in Zhejiang Province

作　　者：莫哲[1] 楼晓明[1] 邹艳[1] 毛光明[1] 王鸳鸯[1] 朱文明[1] 

机构地区：[1]浙江省疾病预防控制中心环境与职业卫生所,杭州310051

出　　处：《中华地方病学杂志》2015年第9期671-675,共5页Chinese Journal of Endemiology

摘　　要：目的了解盐碘含量调整后浙江省人群碘营养水平及甲状腺病情情况。方法2013年4-6月，采用人口比例概率法在浙江省31个县区抽取l650名学龄儿童与620名孕妇作为调查对象，对学龄儿童进行家庭食用盐盐碘含量检测、尿碘含量检测以及甲状腺B超检查，对孕妇进行尿碘含量检测。盐碘含量检测使用直接滴定法；尿碘含量检测使用过硫酸铵消化．砷铈催化分光光度法。结果盐碘含量调整后浙江省碘盐覆盖率为93．20％（1521／1632），合格碘盐食用率为89．71％（1464／1632）；学龄儿童尿碘中位数为178．40μg／L，孕妇尿碘中位数为127．23μg／L；学龄儿童甲状腺肿大率为5．27％（87／1650），甲状腺容积中位数为3．45ml；碘盐含量调整后，8、9、10岁组学龄儿童甲状腺容积岛分位数分别为4．76、5．29和6．36ml，均高于推荐标准（WS276-2007）的4．5、5．0和6ml；并未发现甲状腺容积、甲状腺肿大与尿碘水平的相关关系。结论盐碘含量调整后，浙江省人群尿碘水平回落到适宜水平．说明本次盐碘含量的调整是及时、合适的，但孕妇等特需人群碘营养水平不足的问题应引起注意。[Abstract] Objective To find out the status of iodine nutrition and the goiter of population in Zhejiang Province after adjustment of salt iodine concentration. Methods From April to June 2013, the probability proportionate to size sampling method was applied in 31 countries in Zhejiang Province to select 1 650 school-age children aged 8 - 10 to examine thyroid by B ultrasound, to collect urine and salt samples, and to test the iodine level using the colorimetric titration method and the spectrophotometer method. Six hundred and twenty pregnant women were selected to collect urine samples and urinary iodine was tested by the spectrophotometer method. Results The coverage rate of iodized salt and the consumption rate of qualified iodized salt in Zhejiang Province after adjustment of salt iodine concentration were 93.20% （1 521/1 632） and 89.71% （1 464/1 632）, respectively; and the medians urinary iodine in children and pregnant women were 178.40μg/L and 127.23μg/L, respectively; and the goiter and median thyroid volume were 5.27% （87/1 650） and 3.45 ml, respectively; the P97 thyroid volume of children in Zhejiang Province in the 8, 9 and 10 years old groups （4.76, 5.29, 6.36 ml） were higher than those （4.5, 5.0, 6.0 m]） in the thyroid volume reference （WS 276-2007）; and the correlations between thyroid volume, goiter and urinary iodine were not found. Conclusions After adjustment of salt iodine concentration, the status of iodine nutrition in Zhejiang Province in general is down to optimum level, which indicates that it is appropriate for this adjustment, but the level of iodine nutrition in pregnant women is less than appropriate, which should be pay attention to.

关 键 词：碘 盐类 调整 碘营养 甲状腺肿大 

分 类 号：R599[医药卫生—内科学]