金石饮方剂联合体外冲击波碎石治疗泌尿系结石的疗效及对患者血脂的影响  

Jinshiyin Prescription Combined with Extracorporeal Shock Wave Lithotripsy in Treating Urolithiasis and Its Effect on Serum Lipids in Patients with Urolithiasis

作　　者：郑晓秋[1] 王万东[1] 张继承[1] 熊雨 

机构地区：[1]宜宾市第二人民医院,四川宜宾644000

出　　处：《中国实验方剂学杂志》2015年第18期191-194,共4页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：目的:探讨金石饮方剂联合体外冲击波碎石治疗泌尿系结石的疗效及对患者血脂的影响。方法:120例符合纳入标准的泌尿系结石患者按治疗方案分为对照组(n=60)和观察组(n=60)。对照组给予体外冲击波碎石治疗,观察组在对照组的基础上给予金石饮方剂治疗,并随访1年。观察比较两组患者治疗疗效、复发率、尿培养结果及血脂变化情况。结果:观察组的治疗总有效率为96.7%,明显高于对照组83.3%的总有效率(P<0.05)。随访1年,观察组的复发率为1.7%,明显低于对照组13.0%的复发率(P<0.05)。与对照组相比,观察组治疗后尿培养结果阳性比例降低,血脂指标总胆固醇(total cholesterol,TC),甘油三酯(triglyceride,TG),低密度脂蛋白胆固醇(low-density lipoprotein cholesterol,LDL-C)明显下降,高密度脂蛋白胆固醇(high-density lipoprotein cholesterol,HDL-C)明显增高,比较均有统计学意义(均P<0.05)。结论:金石饮方剂联合体外冲击波碎石是泌尿系结石的一种有效治疗方案,可以提高疗效,减少复发及泌尿系感染,并有效调节血脂,临床上值得进一步研究。Objective： To investigate the clinical efficacy of Jinshiyin prescription combined with extracorporeal shock wave lithotripsy （ESWL） in treating urolithiasis and its effect on serum lipids in patients with urolithiasis. Method： Totally one hundred and twenty cases of eligible urolithiasis patients were divided into two groups according to therapeutic scheme, the control group （n = 60） and the observation group （ n = 60）. The control group was treated with ESWL, and the observation group was treated with Jinshiyin prescription combined with ESWL. The follow-up visit lasted for one year. The curative efficacy, recurrence rate, urine culture result and changes in serum lipid between both groups were observed and compared. Result： The observation group showed a therapeutic efficiency ratio of 96.7% , which was significantly higher than that of 83.3% in the control group （P 〈 0.05）. After the one-year follow-up visit, the recurrence rate in the observation group was 1.7% , which was statistically lower than that of 13.0% in the control group （P 〈 0.05）. Compared with the control group, the observation group showed reductions in the proportion of positive urine culture results, total cholesterol （TC） , triglyceride （TG） and low-density lipoprotein （LDL-C） and increase in high-density lipoprotein （HDL-C） after the treatment, with statistical significance in differences （all P 〈 0.05）. Conclusion： Jinshiyin prescription combined with ESWL in treating urolithiasis is an effective therapeutic scheme, which can increase the therapeutic efficacy, decrease the recurrence rate and urinary infection and effectively regulate serum lipid.

关 键 词：金石饮方剂 体外冲击波碎石 泌尿系结石 血脂 

分 类 号：R287.6[医药卫生—中药学]