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机构地区:[1]成都中医药大学附属医院,四川成都610075 [2]成都中医药大学第三附属医院,四川成都610075 [3]成都中医药大学,四川成都610075
出 处:《成都中医药大学学报》2015年第3期48-51,65,共5页Journal of Chengdu University of Traditional Chinese Medicine
基 金:国家重点基础研究发展计划973计划(编号:2006CB504501)
摘 要:目的:按照CONSORT声明和STRICTA标准,通过实施设计严谨的临床研究,对循胃经远取及局部取穴改善胃肠功能的疗效进行客观评价,为两种经典取穴疗效差异的存在提供依据。方法:采用中央随机,将合纳入标准的FD患者1∶1随机分为循胃经远取组和局部取穴组接受治疗。治疗采用HANS电针仪,治疗频率为1次/d,30 min/次,连续5 d1个疗程,疗程期间休息2 d,共治疗4个疗程,并于疗程结束后第4 w、12 w进行随访。以症状积分和尼平消化不良指数(Nepean Dyspepsia Index,NDI)量表中生活质量部分为评价指标,评价各时间点的疗效。结果:循经远取与局部取穴均能持续改善FD的症状以及提高生活质量,这种改善作用于治疗第2 w即显效,并可持续至治疗结束后12 w。循经远取组针刺对PDS型症状及生活质量的改善优于局部取穴组针刺,而2组对EPS型症状改善疗效相当。循经远取组针刺对生活质量的疗效优势主要体现在认识控制领域、食物领域及干扰领域。结论:循经远取与局部取穴对FD(脏腑疾病的代表)的疗效具有差异性。Objective: To investigate the therapeutic efficacy difference of acupuncture for FD by comparing acupoints on stom- ach meridian with stomach nearby through arranging a randomized controlled trial based on the requirement of CONSORT Statement and STRICTA. Methods: Muhi-center, central-randomanization controlled trial was designed. Patients meeting the inclusion criteria were randomly allocated to group A ( ST34, ST36, ST40, ST42 ) or control group 1 ( non-acupoint puncture ) or group B ( Renl2,BL21 ) . The HAN's acupoint nerve stimulaor was used. The study consisted of a treatment period of 4 weeks (five sessions continuous- ly per week, an interval two days between two courses), and a follow-up period of 12 weeks. Dyspepsic symptoms and the disease-spe- cific quality of life (Nepean Dyspepsia Index, DNI) were evaluated to determine patients' therapeutic efficacy. Results: Both punc- turing at acupoint on the stomach meridian and stomach nearby improved quality of life (QoL) and relieved dyspeptic symptoms continuously, from the 2nd week of treatment to the 12th week after treatment. Puncturing at acupoint on the stomach meridian had significant better effect in improving quality of life and relieving dyspeptic symptoms of PDS subgroup than acupoints nearby, while no significant difference was detected between groups in relieving EPS symptoms. The beneficial effect of acupuncture along stomach meridian in the QoL may depend largely on the improvement in eating/drinking, knowledge/control and interference region. Conclusion: acupuncture along stomach meridian is effective in the treatment of FD and shows superiority over stomach nearby puncture.
关 键 词:功能性消化不良 循经远取 局部取穴 随机对照试验
分 类 号:R245.3[医药卫生—针灸推拿学] R573[医药卫生—中医临床基础]
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