乌头瓜蒌反药组合宜忌条件的实验研究回顾与评析  

Review on the experimental studies of suitable and contraindicant conditions of Chinese medicine antagonism compatibility aconitum and trichosanthes

作　　者：郭岩松[1] 许皖[1] 钟赣生[1] 张建美[1] 柳海艳[1] 欧丽娜[1] 刘佳[1] 赵桐[1] 王思睿[1] 修琳琳[1] 

机构地区：[1]北京中医药大学基础医学院,硕士研究生100029

出　　处：《环球中医药》2015年第9期1025-1030,共6页Global Traditional Chinese Medicine

基　　金：国家重点基础研究发展计划(973计划)(2011CB505300;2011CB505306)

摘　　要：利用中国知网、万方、维普等数据库,系统检索1949～2014年关于中药＂十八反＂中乌头瓜蒌反药组合同用的文献,从检索到的文章中剔除综述及临床研究文章,仅选取实验研究类的文章,总结归纳乌头瓜蒌反药组合的适宜条件和禁忌条件。初步认为乌头瓜蒌反药组合的适宜的条件为：制川乌或制附子配伍全瓜蒌、瓜蒌仁、瓜蒌皮。而乌头瓜蒌反药组合的禁忌条件为：生川乌瓜蒌合用时,瓜蒌相当于临床最大剂量的0.03～6倍,（生川乌一般外用不内服无法进行比较）草乌与瓜蒌1∶1,生附子与瓜蒌1∶1,生川乌与瓜蒌1∶1;生川乌或生附子配伍全瓜蒌、瓜蒌仁、瓜蒌皮。乌头瓜蒌反药组合是否是绝对的配伍禁忌,不能一概而论,宜忌条件也不是固定不变的,单一条件下较难确定某一个条件是适宜的条件还是禁忌的条件,本文归纳出的宜忌条件仅供参考。随着多学科多领域研究的不断深入和发展,关于＂十八反＂的宜忌条件也会更加丰富和充实。This article summarized the suitable conditions and contraindicant conditions of antagonism compatibility aconitum and fructus trichosanthes from the selected experimental research articles by searching “aconitum and fructus trichosanthes compatibility of Chinese medicine Eighteen antagonism”from Wan Fang, CNKI, and VIP database since 1949 to 2014. The suitable conditions： radix aconitum preparata or aconitum with fructus trichosanthes seeds, fructus trichosanthes skin, or Pericarpium trichosanthes. The contrainticant conditions： when using radix aconitum and fructus Trichosanthes, the effect of trichosanthes will be equivalent 0. 03～6 times of clinical maximum dose （radix aconiti is generally not taken orally ） . It depends to say whether these two herbs is contraindicted. The single condition is difficult to be determined as a suitable condition or taboo conditions, and this paper concludes the contraindicant conditions for reference only. With the research of multidisciplinary developing on the“Eighteen antoganisms”thoery, the proper and improper conditions will be more plentiful and substantial.

关 键 词：十八反 乌头 瓜蒌 反药组合 宜忌条件 

分 类 号：R285.5[医药卫生—中药学]