人参藜芦反药组合宜忌条件的实验研究回顾与评析  

Review on the experimental studies of suitable and contraindicant conditions of Chinese medicine antagonism compatibility ginseng and veratrum nigrum

作　　者：郭岩松[1] 许皖[1] 钟赣生[1] 张建美[1] 柳海艳[1] 欧丽娜[1] 刘佳[1] 赵桐[1] 王思睿[1] 

机构地区：[1]北京中医药大学基础医学院,硕士研究生100029

出　　处：《环球中医药》2015年第9期1064-1069,共6页Global Traditional Chinese Medicine

基　　金：国家重点基础研究发展计划(973计划)(2011CB505300;2011CB505306)

摘　　要：利用中国知网、万方、维普、Pub Med等数据库,系统检索1949～2014年关于中药＂十八反＂中人参藜芦反药组合同用的文献,从检索到的文章中剔除综述及临床研究文章,仅选取实验研究类的文章,总结归纳人参藜芦反药组合的适宜条件和禁忌条件。结合现有的实验成果,未能归纳出人参藜芦反药组合的适宜的条件,初步认为人参藜芦反药组合的禁忌条件为：人参藜芦合用,人参相当于临床最大剂量的2～10倍,藜芦相当于临床最大剂量的10～30倍;藜芦为临床最高剂量的一半,而人参为临床剂量的4～8倍;人参与藜芦配伍比例小于100∶1;红参配伍黑藜芦,生晒参配伍黑藜芦。人参藜芦入药方式、煎煮时间和复方应用因为相关研究较少或不够全面,未能归纳出禁忌条件。人参藜芦反药组合是否是绝对的配伍禁忌,不能一概而论,宜忌条件也不是固定不变的,单一条件下较难确定某一个条件是宜的条件还是忌的条件,随着多学科、多领域研究的不断深入和发展,宜忌条件也会更加丰富和充实。This article summarized the suitable conditions and contraindicant conditions of antagonism compatibility ginseng and veratrum nigrum from the selected experimental research articles by searching“ginseng and veratrum nigrum compatibility of Chinese medicine Eighteen antagonism” from Wan Fang, CNKI, and VIP database since 1949. There is not enough data to summarize suitable conditions. While the contraindicant conditions are as below：the dose of ginseng is equivalent to the maximum clinical dose of 2～10 times, and the dose of veratrum nigrum is equivalent to clinical maximum dose of 10 ～30 times;the dose of ginseng is equivalent to the maximum clinical dose of 4～8 times, and the dose of veratrum nigrum is equivalent to half clinical maximum;the ratio of ginseng with veratrum nigrum is less than 100：1;red ginseng with black veratrum;ginseng with black veratrum. There are contradictory to each other due to the experimental results. Whether the two herbs are absolute incompatibility or not can not be generalized and improper and proper conditions are relative, under a single condition is difficult to identify a particular condition or conditions suitable or not. With the deepening and developing studies, proper and improper conditions will be more enriched and abundent.

关 键 词：十八反 人参 藜芦 反药组合 宜忌条件 

分 类 号：R285.5[医药卫生—中药学]