含吡啶联喹啉羧酸新型配体的合成和表征  

Synthesis and characterization of novel ligands containing pyridine associated quinolinecarbocylates

作　　者：白仁青卓玛 李凯[1] 兰帅[1] 高文涛[1] 

机构地区：[1]渤海大学超精细化学品研究所,辽宁锦州121000

出　　处：《化学研究与应用》2015年第9期1354-1360,共7页Chemical Research and Application

摘　　要：以4-乙酰基吡啶(2)、2,6-二乙酰基吡啶(3)为底物分别与靛红及取代靛红(1a-1g)在KOH做催化剂的条件下,以10%的乙醇溶液作为溶剂进行反应,以41.4%-90.5%的产率得到了结构新颖的含氮联喹啉酸有机配体(4a-4g)和(5a-5g),它们的结构均通过红外光谱、核磁共振氢谱、核磁共振碳谱和质谱得以证实。以上制备过程具有反应条件温和、后处理简单、环境友好等优点,为制备含吡啶联喹啉羧酸新型配体提供了简单有效的方法。4-Acetyl（2）and 2,6-diacetyl pyridine（3）were chosen as the substrates to react with the isatin and substituted isatins （1a-1g）with the presence of KOH as catalyst in 10%aq. ethanol solution to afford structurally novel pyridine-containing quinoline-carboxylic acid ligands in the yields ranging 41. 0%-90. 5%. The structures of all the newly-synthesized compounds were confirmed by IR,MS,^1 H and ^13 C NMR spectra. The above procedures for the preparation of 4a-4g and 5a-5g had the advantages such as mild reaction conditions,simple work-up,and environmental-friendly reaction medium,and thus could be used as a simple and effective approach for the preparation of pyridine-quinoline-carboxylic acid ligands.

关 键 词：靛红 Pfitzinger反应 配体 合成 

分 类 号：O641[理学—物理化学]