碳纳米管固定化酶  

Enzyme Immobilized on Carbon Nanotubes

作　　者：万晓梅[1] 张川[1] 余定华[1] 黄和[1] 胡燚[1] 

机构地区：[1]南京工业大学生物与制药工程学院材料化学工程国家重点实验室,南京210009

出　　处：《化学进展》2015年第9期1251-1259,共9页Progress in Chemistry

基　　金：国家高技术研究发展计划(No.2011AA02A209);国家杰出青年科学基金项目(No.21225626)资助~~

摘　　要：在固定化酶技术中,载体材料的选择至关重要,碳纳米管作为一种新型高效的酶固定化载体,具有较大的比表面积、有序的纳米孔道结构、良好的力学/电学/热学性能、突出的化学稳定性、生物相容性和可控的表面官能化修饰等优良特性,应用日益广泛。本文重点介绍了水解酶、氧化还原酶等具有重要工业应用价值的酶在碳纳米管上的固定化研究现状,探讨了载体的表面修饰和固定化方式对固定化酶的酶学性质的影响,并对碳纳米管固定化酶的发展前景进行了展望。In the technology of enzyme immobilization, the choice of carrier material is very important for the catalytic performance of enzyme. As a new type of high efficient enzyme immobilization carrier with larger specific surface area, ordered nano pore structure, good mechanical/electrical/thermal performance, outstanding chemical stability, biocompatibility and controllable surface functional modifications, carbon nanotubes are used more and more extensively. The recent research progress of enzyme immobilization on carbon nanotubes is reviewed in this paper, focusing on the immobilization of hydrolases and oxido-reductases, which have important industrial application value. The influence of surface modification of carrier and immobilization methods on the catalytic properties of immobilized enzymes is introduced. The outlook of potential applications of enzyme immobilization on carbon nanotubes is also prospected.

关 键 词：碳纳米管 固定化 酶 水解酶 氧化还原酶 

分 类 号：O613.7[理学—无机化学] Q81[理学—化学]