不规则抗体特异性不明确患者的输血疗效及安全性评估  

Transfusion efficacy and safety evaluation in patients with non-specificity irregular antibody

作　　者：杨璐[1] 陈麟凤[1] 于洋[1] 王彦[1] 关晓珍[1] 孙晓琳[1] 张晓娟[1] 马春娅[1] 封彦楠 王金慧[1] 汪德清[1] 

机构地区：[1]中国人民解放军总医院输血科,北京100853

出　　处：《国际检验医学杂志》2015年第18期2630-2632,共3页International Journal of Laboratory Medicine

基　　金：卫生部行业专项基金项目(NO.201002005)

摘　　要：目的评估不规则抗体特异性不明确患者的输血疗效及安全性。方法通过分析19例产生无特异性不规则抗体的贫血患者的输血疗效及输血后不良反应的发生情况,对随机选取的与患者ABO同型的献血员进行交叉配血,评价在微柱凝胶法与盐水法配血均相合的情况下进行输注的输血疗效及安全性。结果 19例患者产生的无特异性不规则抗体均为IgG类不规则抗体;均进行红细胞输注,其中输注有效率为73.7%,部分有效率为26.3%,无效率为0.0%。所有输血病例均无迟发型溶血性输血反应发生。结论对于血清不规则抗体特异性不明确的患者,在微柱凝胶法与盐水法配血均相合的情况下进行输注是安全、有效的。Objective To evaluate the transfusion efficacy and safety of patients with non‐specificity irregular antibodies .Meth‐ods A total of 19 cases of patients with non‐specificity irregular antibodies were analyzed ,then the transfusion efficacy and the in‐cidences of adverse transfusion reactions were investigated .Blood donor samples with the same ABO blood type of patients were randomly collected ,then blood cross‐matching was carried out .And the transfusion efficacy and safety of patients with non‐specific‐ity irregular antibody were evaluated when compatible blood were found by using both micro‐column gel technique and saline meth‐od .Results The non‐specificity irregular antibodies of the 19 cases of patients all were IgG irregular antibodies .The erythrocyte transfusion was carried out in the 19 cases of patients ,the total efficiency rate ,partial efficiency rate and inefficiency rate was 73 .7% ,26 .3% and 0 .0% ,respectively .No delayed hemolytic transfusion reactions were observed in any patient .Conclusion For patients with non‐specificity irregular antibodies ,the blood transfusion could be efficacy and safety when compatible blood samples are confirmed by using both micro‐column gel technique and saline method .

关 键 词：不规则抗体 抗体特异性 输注疗效 输血安全 

分 类 号：R446.6[医药卫生—诊断学]