西安市健康成人乙、丙型肝炎病毒感染状况及流行病学分析  

Investigation on infection status of hepatitis B virus and hepatitis C virus in healthy adult group in Xi′an City

作　　者：张涛[1] 王菁[1] 吴永昌[1] 邹海[1] 金亚莉[1] 邢瑞青[1] 刘杨[1] 彭道荣[1] 

机构地区：[1]第四军医大学西京医院全军检验医学研究所,陕西西安710032

出　　处：《国际检验医学杂志》2015年第18期2656-2658,共3页International Journal of Laboratory Medicine

摘　　要：目的调查西安市健康成人乙型肝炎病毒（HBV）和丙型肝炎病毒（HCV）的感染状况,为乙、丙型肝炎防治及健康教育提供依据。方法采用多阶段分层随机抽样在西安市10个社区抽取1 052例健康成人,检测HBV 6项血清学标志物和抗-HCV抗体,分析HBV及HCV感染的分布特征。结果共检出乙型肝炎表面抗原（HBsAg）阳性37例,总阳性率为3.52%,男性阳性率为4.08%,女性阳性率为3.07%,男、女比较差异无统计学意义（P〉0.05）;除30～〈40岁与40～〈50岁年龄段男性,其余各年龄段及各年龄段性别间HBsAg阳性率比较差异均无统计学意义（P〉0.05）;检出HBsAg、乙型肝炎e抗体（HBeAb）和乙型肝炎核心抗体（HBcAb）阳性31例,阳性率为2.95%,单乙型肝炎表面抗体（HBsAb）阳性率为54.18%,各相同血清学模式男、女所占百分率比较,差异均无统计学意义（P〉0.05）。检出抗-HCV抗体阳性9例（0.86%）,男性阳性率为0.64%,女性阳性率为1.02%,男、女阳性率差异无统计学意义（P〉0.05）。结论西安市健康成人HBV、HCV感染率较低,但仍需进一步加强健康教育,定期进行常规传染病的监测与疫苗接种,以控制乙、丙型肝炎。Objective To investigate the infection status of hepatitis B virus（HBV） and hepatitis C virus（HCV） in healthy adult in Xi′an ,in order to provide references for hepatitis prevention and health education .Methods A total of 1 052 healthy adults from 10 communities in Xi′an were collected by using multistage stratified random sampling method .HBV serum markers and anti‐HCV antibody were detected ,and characteristics of distribution of HBV and HCV infection were analysed .Results A total of 37 adults were observed with positive hepatitis B surface antigen（HBsAg） ,the total positive rate was 3 .52% ,and the positive rate of male and female was 4 .08% and 3 .07% respectively ,no statistically significant difference was found between male and female（P〉0 .05） .Apart from male adults aged 30 - 〈 40 and 40 - 〈 50 ,there were no statistically significant differences between each age groups in male and female ,and between female and male in the same age groups（P〉 0 .05） .A total of 31 adults were observed with HBsAg ,hepatitis B e antibody （HBeAg）and hepatitis B core antibody（HBcAb） positive ,the positive rate was 2 .95% .The positive rate of hepatitis B surface antibody（HBsAb） was 54 .18% .Serological patterns between different gender had no statistically signifi‐cant differences（P〉0 .05） .A total of 9 adults（0 .86% ） were observed with positive anti‐HCV antibody ,and the positive rate of male and female was 0 .64% and 1 .02% respectively ,no statistically significant difference was found between male and female（P〉0 .05） .Conclusion Healthy adults in Xi′an have relatively low infection rates of HBV and HCV ,while for the control of hepatitis B and hepatitis C ,further strengthening the health education ,improving awareness of prevention and routine monitoring infectious dis‐eases and vaccination may still be necessary .

关 键 词：乙型肝炎病毒 丙型肝炎病毒 健康成人 感染率 流行病学 

分 类 号：R512.6[医药卫生—内科学] R446.6[医药卫生—临床医学]