科玛嘉念珠菌培养基鉴别念珠菌的系统评价  

CHROMagar Candida medium for identification of Candida species:a systematic review

作　　者：邢献国[1] 刘辉[1] 孟岩[1] 

机构地区：[1]首都医科大学丰台教学医院检验科,北京100070

出　　处：《国际检验医学杂志》2015年第18期2688-2690,共3页International Journal of Laboratory Medicine

摘　　要：目的评价科玛嘉念珠菌培养基鉴别常见致病性念珠菌的准确性。方法检索MEDLINE、EMBase、中国生物医学文献数据库(CBM)、中文科技期刊全文数据库(CSJD)、中国期刊全文数据库(CJFD)等数据库,并通过其他途径全面收集文献,采用诊断性试验准确性质量评价工具(QUADAS)标准评价文献质量,用Meta-Disc软件制作综合受试者工作特征(SROC)曲线,评价科玛嘉显色培养基鉴别常见致病性念珠菌的准确性。结果纳入符合标准的文献7篇。7篇文献均报道了科玛嘉念珠菌培养基检测白色念珠菌的准确性,总灵敏度和总特异度分别为98.3%、98.8%,SROC曲线下面积(AUC)为0.998 0;6篇文章报道了科玛嘉念珠菌培养基检测热带念珠菌的准确性,总灵敏度和总特异度分别为92.5%、99.8%,AUC为0.998 3;5篇文章报道了科玛嘉念珠菌培养基检测光滑念珠菌的准确性,总灵敏度和总特异度分别为98.3%、98.7%,AUC为0.996 8。结论科玛嘉培养基能快速鉴定临床常见念珠菌,鉴定结果准确可靠。Objective To evaluate the accuracy of CHROMagar Candida medium in identifying common Candida species .Meth‐ods Articles were extensively collected by searching the databases of MEDLINE and EMBase ,the Chinese Biomedical Database （CBM ） ,the Chinese Scientific Journals Database （CSJD） ,the Chinese Journal Full Text Database （CJFD） and through other ways . The qualities of these articles were assessed by using the quality assessment of diagnostic accuracy studies（QUADAS） .At last , summary receiver operating characteristic （SROC） curve was performed by the Meta‐Disc software ,so as to summarize diagnostic accuracy of CHROMagar Candida medium in identifying common Candida species .Results A total of 7 articles meeting all criteria were enrolled in this study .All 7 articles reported the accuracy of CHROMagar Candida medium in identifying the Candida albi‐cans ,the pooled sensitivity and specificity was 98 .3% and 98 .8% respectively ,and area under SROC curve （AUC） was 0 .998 0 .A‐mong them ,6 articles reported the accuracy of CHROMagar Candida medium in identifying Candida tropicalis ,the pooled sensitivity and specificity was 92 .5% and 99 .8% respectively ,and the AUC was 0 .998 3 .Among them ,5 articles reported the accuracy of CHROMagar Candida medium in identifying Candida Glabrata ,the pooled sensitivity and specificity was 98 .3% and 98 .7% respec‐tively ,and the AUC was 0 .996 8 .Conclusion CHROMagar Candida medium could quickly identify clinical common Candida species and results are reliable .

关 键 词：科玛嘉念珠菌培养基 念珠菌 系统评价 综合受试者工作特征曲线 

分 类 号：R446.5[医药卫生—诊断学]