响应面优化钙离子沉淀分离连翘槲皮素  

Optimization on Precipitation Separation Technology of the Quercetin in Forsythia by Response Surface Methodology

作　　者：符智荣[1] 李雪峰[1,2] 欧阳玉祝[2] 陈实[2] 

机构地区：[1]吉首大学师范学院,湖南吉首416000 [2]吉首大学化学化工学院,湖南吉首416000

出　　处：《广东化工》2015年第18期35-37,79,共4页Guangdong Chemical Industry

基　　金：植物资源保护与利用湖南省高校重点实验室开放基金(No:13jdzb094)

摘　　要：在单因素实验基础上,利用响应面法对影响钙离子沉淀分离连翘槲皮素的主要因素进行了优化,建立了影响因素与提取率之间的函数关系。实验结果表明,25 m L提取液中,在石灰水用量62.5 m L,沉淀温度63.5℃,沉淀时间28 min条件下沉淀分离,槲皮素提取率为3.214%,实验结果与模型预测值相符。Influence factor of Calcium ion precipitation separation quercetin in forsythia were optimized by Response surface methodology （RSM） based on single-factor experiment. The function relationship between influencing factors and response values was established. The results show that using 62.5 mL clarified limewater as precipitator, for 63.5℃ purification 28 min, extraction rate of the quercetin is 3.214 %, which was well matched with the predicted content.

关 键 词：连翘 槲皮素 沉淀 响应面法 

分 类 号：TQ134.11[化学工程—无机化工]