双手搐搦-低钙血症-肌酶升高  

Carpal spasms-hypocalcemia-elevated serum creatine kinase

作　　者：王文博[1] 胡莹莹[2] 姜艳[1] 李梅[1] 夏维波[1] 邢小平[1] 王鸥[1] 孟迅吾[1] 

机构地区：[1]中国医学科学院北京协和医学院北京协和医院内分泌科国家卫生和计划生育委员会内分泌重点实验室,北京100730 [2]中国医学科学院北京协和医学院北京协和医院检验科,北京100730

出　　处：《中华骨质疏松和骨矿盐疾病杂志》2015年第3期246-250,共5页Chinese Journal Of Osteoporosis And Bone Mineral Research

基　　金：国家自然科学基金(81100559;81270873);国家临床重点专科建设项目(WBYZ2011-873)

摘　　要：低钙性肌病是甲状旁腺功能减退症(以下简称甲旁减)的罕见并发症之一。本文报道了1例特发性甲旁减导致肌酸激酶(creatine kinase,CK)升高。患者为23岁男性,因间断双手搐搦10年入院,入院前2个月有一次癫痫样发作,实验室检查示血钙和甲状旁腺素水平降低,血清CK水平明显升高,给予钙剂及维生素D补充治疗后,随血钙水平上升,CK逐渐下降。本文同时对甲旁减合并肌酶升高的相关文献进行了复习和总结。Hypocalcemic myopathy is a rare manifestation of hypoparathyroidism. Here we reported a case of hypocalcemia due to idiopathic hypoparathyroidism associated with elevated serum creatine kinase level. A 23-year-old man suffered from intermittent carpal spasms for 10 years and he had seizure 2 months before the hospitalization. Laboratory tests showed decreased serum calcium and parathyroid hormone levels accompanied with increased serum creatine kinase concentration. With the treatment with calcium and vitamin D supplementation,the serum creatine kinase levels decreased gradually accompanied by the improvement of hypocalcemia. The related literature was reviewed.

关 键 词：甲状旁腺功能减退症 低钙血症 肌酶升高 

分 类 号：R445[医药卫生—影像医学与核医学]