棕色脂肪和米黄色脂肪研究进展  

Progress on Brown Adipose Tissue and Beige Adipose Tissue

作　　者：刘向东[1] 李戡[1] 刘文忠[1] 张建新[1] 任有蛇[1] 张春香[1] 赵俊星[1] 

机构地区：[1]山西农业大学动物科技学院,山西太谷030801

出　　处：《动物医学进展》2015年第10期95-99,共5页Progress In Veterinary Medicine

基　　金：国家自然科学基金项目(31402053);山西省回国留学人员科研资助项目(2014-039);山西农业大学科技创新基金项目(20132-01)

摘　　要：脂肪组织不仅是机体能量储存的主要场所,也是重要的内分泌器官。根据脂肪颜色的不同,动物脂肪组织可分为白色脂肪(WAT)、棕色脂肪(BAT)和米黄色脂肪(Beige)。WAT以甘油三酯的形式储存能量,而BAT是动物非颤抖性产热的主要场所。在一定外界环境刺激下,WAT可以生成一种与BAT功能类似的细胞,称之为Beige细胞。论文对棕色脂肪和米黄色脂肪的功能、增殖与分化机制进行了综述,并对其在畜牧业中的应用进行了展望。The adipose tissue is recognized not only as the energy storage site,but also as an important en-docrine organ that plays important role in whole body energy homeostasis.According to their appearance, adipose tissues can be divided into white adipose tissue （WAT）,brown adipose tissue （BAT）and Beige ad-ipose tissue.The main function of WAT is for energy storage,while the BAT is mainly responsible for heat generation.Under certain environmental stress,WAT may convert into BAT-like adipocytes,named Beige cells.In present review,we summarized the functions and differentiation mechanisms of both BAT and WAT,and predict their application in husbandry industry.

关 键 词：棕色脂肪 米黄色脂肪 转录因子 小RNA 

分 类 号：S852.21[农业科学—基础兽医学]