腹腔镜辅助与开腹结直肠癌根治术治疗Ⅱ、Ⅲ期结直肠癌效果比较  

Security of laparoscopic surgery vs.conventional open surgery for stage Ⅱ or Ⅲ colorectal cancer

作　　者：徐飞鹏[1] 许庆文[1] 鲁珏[1] 刘春安[1] 黄哲[1] 林琳[1] 王玮尉[1] 

机构地区：[1]广东医学院附属医院胃肠外科,湛江524001

出　　处：《中华实验外科杂志》2015年第9期2253-2254,共2页Chinese Journal of Experimental Surgery

基　　金：卫生部医药卫生科技发展研究中心课题项目（W2013R07）

摘　　要：目的 观察比较腹腔镜和开腹结直肠癌根治术对Ⅱ、Ⅲ期结直肠癌患者的创伤程度及安全性的影响.方法 96例结直肠癌患者随机分为2组,其中腹腔镜辅助手术组（腹腔镜组,n=48）及开腹手术组（开腹组,n=48）,比较两组的患者在手术过程中的手术时间、出血量、切口总长度、住院时间、术后肛门首次排气时间等情况.结果 腹腔镜组出血量[（92.15±12.75） ml]、切口长度[（6.45±1.07） cm]、住院时间[（11.27±1.80）d]及术后排气时间[（3.39±0.37）d]等指标均优于开腹组[（152.70±24.25） ml、（18.61±1.32） cm、（17.88±1.26）d、（4.53±0.70）d],两组比较差异均有统计学意义（P＜0.05）.结论 腹腔镜结直肠癌根治术安全可行,具有患者创伤小、康复快、住院时间短的等优点.Objective To observe and compare the trauma degree and security after laparoscopic surgery （LS） vs.conventional open surgery （OS） for stage Ⅱ or Ⅲ colorectal cancer （CRC）.Methods Ninety-six cases of stage Ⅱ or Ⅲ CRC with sepsis were divided into LS group （n =48） and OS group （n =48） according to the random double blind method.The related outcomes of two groups were compared,including operating time,intraoperative blood loss,length of incision,postoperative hospital stay,exhaust time.The changes in serum inflammatory index and immune indexes were analyzed on the day before and the 1 st and 5th day after surgery.Results Intraoperative blood loss [（92.15 ± 12.75） ml],length of incision [（6.43 ± 1.07） cm],postoperative hospital stay [（11.27 ± 1.80） days] and exhaust time [（3.39 ±0.37） days] in LS group were significantly different from those in OS group [（152.70 ± 24.25） ml,（18.61 ±1.32） cm,（17.88 ±1.26） days and （4.53 ±0.70） days] （P＜0.05 for all）.Conclusion Laparoscopic technology is safe and feasible in treating colorectal carcinoma,with less trauma,quicker recovery,shorter hospital stay,etc..

关 键 词：结直肠癌 腹腔镜技术 

分 类 号：R726.5[医药卫生—儿科]