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作 者:王郁[1]
机构地区:[1]辽宁省阜新矿业集团总医院耳鼻咽喉科,辽宁阜新123000
出 处:《航空航天医学杂志》2015年第9期1062-1065,共4页Journal of Aerospace medicine
摘 要:目的探讨慢性鼻窦炎合并鼻息肉患者手术后应用罗红霉素联合丙酸氟替卡松治疗对患者治疗效果的影响作用。方法将收治的88例慢性鼻窦炎合并鼻息肉患者采用随机数字表法分为联合组和对照组各44例,两组术后均给予丙酸氟替卡松治疗,联合组加用罗红霉素,观察两组患者术后症状、临床疗效等指标的差异。结果联合组的愈合时间11.1±2.7(天)、住院时间4.4±1.8(天)、延迟愈合率13.64%均显著的低于对照组的愈合时间13.3±2.8(天)、住院时间5.1±1.6(天)、延迟愈合率31.82%且差异具有统计学意义(P<0.05),两组间术后发生鼻腔粘连的情况差异不具有统计学意义(P>0.05)。术后2周联合组的渗出物、疼痛、创缘水肿评分均显著的低于对照组且差异具有统计学意义你(P<0.05);术后两组患者的渗出物、疼痛、创缘水肿评分较术后第3 d均显著的降低(P<0.05)。术后3个月联合组和对照组的鼻内镜评分较术前均显著的降低(P<0.05),术后联合组的鼻内镜评分显著低于对照组、上皮化率100%显著的高于对照组的84.09%且差异具有统计学意义(P<0.05)。结论慢性鼻窦炎合并鼻息肉患者手术后应用罗红霉素联合丙酸氟替卡松治疗能偶更有效的改善患者的临床症状体征,提高治疗效果。Objective To explore the chronic sinusitis with nasal polyps surgery after application of roxithromycin combined with propionic acid fluoride effect on treatment effect of patients treated with fluticasone propionate. Methods Will of the ear, nose and throat hospital were 88 cases of chronic sinusitis and nasal polyps in patients with the random number table method is divided into combination group and control group, 44 cases in each group. After operation in two groups were given fluorine propionic acid and fluticasone propionate treatment, combined group were treated with rox- ithromycin to observe differences in two groups of patients with postoperative symptoms, clinical and other indicators. Results Joint group of healing time 11.1 _+ 2.7 ( d), hospitalization time (4.4 _+ 1.8 ( d), delayed healing rate was 13.64% were significantly below the control group healing time is 13.3 _+2. 8 (d), hospitalization time 5. 1 _+ 1.6(d), delayed healing rate 31.82% and the difference was statistically significant ( P 〈 0.05 ). Between the two groups after operation occurred the differences in adhesion of nasal cavity was not statistically significant ( P 〉 0.05 ). After 2 weeks of combination group exudate, pain, a margin of edema scores were significantly lower than control group and the differ- ence was statistically significant you ( P 〈 0. 05 ) ; after operation of two groups of patients with exudate, pain, a margin of edema score compared with postoperative 3 days were significantly reduced ( P 〈 0. 05 ). Postoperative 3 months com- bined group and control group of nasal endoscopic score compared with the preoperative were significantly decreased ( P 〈 0.05 ) and combined group after operation of nasal endoscopy score was significantly lower than that of control group, epithelialization rate 100%, significantly higher than control group of 84. 09% and the difference was statistically signifi- cant (P 〈 0. 05). Conclusions Chronic sinusitis with nasal pol
关 键 词:慢性鼻窦炎 鼻息肉 罗红霉素 丙酸氟替卡松 治疗效果
分 类 号:R765.2[医药卫生—耳鼻咽喉科]
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