乌鲁木齐地区正常人群血清TSH参考区间的建立  

Research on TSH Reference Interval of Normal Population in Urumqi Area

作　　者：王新玲[1] 木尼拉.阿不都乃依木 陈翔[1] 徐子奇[1] 郭艳英[1] 艾合买提江.吐呼提 热孜万古丽.乌斯曼[1] 赵红丽[1] 

机构地区：[1]新疆维吾尔自治区人民医院内分泌科,新疆乌鲁木齐830001

出　　处：《标记免疫分析与临床》2015年第9期839-841,878,共4页Labeled Immunoassays and Clinical Medicine

基　　金：国家自然科学基金委员会资助项目(81260127);新疆乌鲁木齐市天山区科学技术计划项目(20120101);新疆自治区人民医院项目(20110102)

摘　　要：目的建立乌鲁木齐地区正常人群血清促甲状腺激素(TSH)参考区间。方法按美国国家临床生化协会(NACB)指南中关于甲状腺疾病诊断的筛选要求,在乌鲁木齐市某一社区筛选体格检查及相关实验室检查及甲状腺超声均正常的健康人893名,测定血清TSH。结果青年组血清TSH水平低于中年组及老年组,差异有统计学意义(P<0.01),而中年组及老年组间差异无统计学意义。女性TSH水平在同年龄层间比较均高于男性(分别为P<0.001、P<0.05、P<0.05)。汉族TSH水平在同性别比较中高于维族(男性P<0.05,女性P<0.001)。结论 TSH水平正常范围女性高于男性,汉族高于维族。Objective To establish normal reference interval of serum thyroid stimulating hormone （TSH） in Urumqi area. Methods According to the NACB guide line for thyroid disease diagnosis requirements, 893 apparently healthy individuals （359 male, 534 female ） age of 18 to 84 from one of Urumqi community were involved in this study. The serum TSH levels were detected and thyroid ultrasound examination was carried out. Results The serum TSH levels in youth group were significantly lower than that of middle and older-aged group （P 〈0.01 ）. There was no significantly difference on TSH level between middle age and elder-aged group. The levels of serum TSH in female were higher than that of male in the same age range people （ P 〈 0. 001 ）. Regardless of gender differences, the levels of serum TSH in Han nationality were higher than that of Uygur （ P 〈 0.05 for male, P 〈 0. 001 for female）, Conclusion The reference interval of serum TSH levels in female is higher than that of male ,and Han nationality is higher than that of Uygur nationality.

关 键 词：乌鲁木齐地区 TSH 正常参考区间 

分 类 号：R446.11[医药卫生—诊断学]