黄芪的有效成分提取与纳滤提取应用分析  

Active Ingredients Extracted and Nanofiltration Application in Astragalus Extract

作　　者：郭立忠[1] 吴镝[1] 

机构地区：[1]长春中医药大学附属医院,130021

出　　处：《中国卫生标准管理》2015年第25期141-142,共2页China Health Standard Management

基　　金：中国中医药管理局.全国中药特色技术传承人才培训项目

摘　　要：目的分析黄芪的有效成分提取和纳滤提取的应用,对传统的黄芪提取工艺进行改进。方法将黄芪多糖、总皂甙作为实验对象,使用正交实验设计并用极差分析法分析数值,对比不同提取温度、时间和次数对成分含量的影响,并在水煮醇沉提取工艺中加入了纤维素酶,比较纳滤、蒸发方法的效果。结果实验表明温度<80℃、提取2次且每次60 min的纳滤浓缩提取是黄芪水提的最佳工艺。结论相比较传统水煮醇沉提取法,黄芪的纳滤浓缩提取工艺在经济、技术上有很强的优越性,在指导制剂生产、临床应用中具有一定的推广价值。Objective To analyze the active ingredients of astragalus diarrhea extraction and nanofiltration extracted application,astragalus traditional extraction process improvements. Methods APS,saponins as subjects,the use of orthogonal experimental design and analysis of numerical range analysis by comparing the effects of different extraction temperature,time and number of ingredients,and the extraction process in boiling alcohol shen added effect of cel ulase,nanofiltration comparison,the evaporation method. Results The experimental results showed that the temperature 〈 80 ℃, extracting 2 times,and each time 60 min nanofiltration concentrated extract was the optimum water extraction of astragalus. Conclusion Compared to traditional boiling alcohol precipitation extraction,astragalus of nanofiltration extraction process in the economic,technical y strong advantages,it has some promotional value in guiding the preparation of manufacturing,clinical applications.

关 键 词：黄芪 有效成分 纳滤提取 蒸发浓缩 

分 类 号：R28[医药卫生—中药学]