住院2型糖尿病患者血浆渗透压升高的危险因素分析  

Analysis on Risk Factors of Plasma Hypertonicity among Hospitalized Type 2 Diabetes

作　　者：陈利鸿[1] 程莉惠[2] 李莎[1] 李华琦[1] 傅徐泉[1] 刘宜东[1] 钟晓卫[1] 

机构地区：[1]四川省成都市第三人民医院内分泌及代谢病科,610031 [2]核工业四一六医院检验科

出　　处：《医学理论与实践》2015年第17期2292-2293,共2页The Journal of Medical Theory and Practice

摘　　要：目的:探讨住院2型糖尿病患者血浆渗透压升高的危险因素。方法:纳入住院的2型糖尿病患者639例(男328例,女311例)。收集患者入院时血糖、血钾、血钠、糖化血红蛋白、尿微量白蛋白/肌酐、糖尿病病程等数据。采用多因素Ordinal Regression分析2型糖尿病患者的有效血浆渗透压的危险因素。结果:住院糖尿病患者血浆渗透压升高的比例占到72.3%,并且高渗透压的患者比例达到了43.3%。Ordinal Regression分析显示血糖水平、年龄、糖化血红蛋白与血浆渗透压的升高呈正相关(P<0.05);糖尿病病程与血浆渗透压升高呈负相关(P<0.05);未发现性别、糖尿病肾病与血浆渗透压升高相关(P>0.05)。结论:住院2型糖尿病患者血浆渗透压升高的患者较多;血糖水平、年龄、糖化血红蛋白水平是2型糖尿病高血浆渗透压的危险因素。Objective：To investigate the risk factors of plasma hypertonicity among hospitalized Type 2diabetes.Methods：639type 2diabetes patients in hospital were enrolled.Blood and urine sample were collected on admission,and blood glucose,serum potassium,sodium,glycosylated hemoglobin,urine albumin/creatine was tested.Duration of diabetes was also obtained.Ordinal Regression model was used to predict the risk factors of plasma tonicity.Results：Elevated plasma tonicity was observed in 72.3% of the in-patient diabetic patients,and ratio of high tonicity is 43.3%.Blood glucose level,age,glycosylated hemoglobin,were related positively with hypertonicity（P〈0.05）.Duration of diabetes was related negatively with tonicity（P〈0.05）.No relationship was observed between gender,diabetic nephropathy with plasma tonicity（P〉0.05）.Conclusion：Blood glucose level,age,and glycosylated hemoglobin,were risk factors of hypertonicity.

关 键 词：糖尿病 渗透压 危险因素 

分 类 号：R587.1[医药卫生—内分泌]