八月桂花籽的化学成分研究  

Studies on the Chemical Components of the Seeds of Osmanthus fragrans ‘Bayuegui'

作　　者：乔春林[1] 秦玉琴[1] 张春燕[1] 张旭[1] 白雪梅[1] 周奋进[1] 李珊忆 黄静[1] 

机构地区：[1]四川大学华西药学院,四川成都610041

出　　处：《合成化学》2015年第9期854-857,共4页Chinese Journal of Synthetic Chemistry

摘　　要：采用硅胶柱色谱法和重结晶法对八月桂花籽的化学成分进行了研究。从八月桂花籽的95%乙醇提取物中分离出9个单体化合物[熊果酸（1）,苯甲酸（2）,对羟基苯乙醇（3）,β-谷甾醇（4）,β-胡萝卜苷（5）,红景天苷（6）,红景天苷酯（7）,（-）-methylelenolate（8）和4,4＇-二甲基-3,3＇-二甲氧羰基-5,5＇-（1″-甲基-1,3″-丙基）-二吡啶（9）],其结构经1H NMR,13C NMR,DEPT,HMQC和HMBC确证。1~9均为首次从八月桂花籽中分离得到,其中7~9为首次以天然产物形式分离得到。The chemical components from the 95 % ethanol extract of the seeds of Osmanthus fragrans ＇Bayuegui＇ were investigated by the silica gel, RP-C18, Sephadex LH-20 colunm chromatographies and restallization method. Nine compounds were obtained and identified as ursolic acid（ 1 ）, benzoic acid （2）, p-hydroxyphenyl alcohol （ 3 ）, β-sitosterol （ 4 ）, fl-daucosterine （ 5 ）, salidroside （ 6 ）, β-D- glucopyranoside-2-（4-hydroxyphenethyl） -6-acetate （ 7 ）, （ - ） -methylelenolate （ 8 ）, 4,4＇-dimethyl- 3,3 ＇-dimethoxycarbonyl-5,5 ＇- （ 1 ＂-methyl-1 ＂, 3＂-propyl ） dipyridine （ 9 ）. The structures were confirmed by ^1H NMR, ^13C NMR, DEPT, HMQC and HMBC. 1 -9 were isolated from the title plant for the first time and compounds 7 - 9 were isolated as a natural form for the first time.

关 键 词：木犀科 八月桂花 种子 分离 化学成分 

分 类 号：R284.2[医药卫生—中药学]