蛛网膜下腔出血后肌钙蛋白Ⅰ变化研究进展  

Research Progress in Variation of cardiac Troponin Ⅰ after Subarachnoid Hemorrhage

作　　者：王治龙[1] 张立敏[1] 邹玉梅[1] 戚思华[1] 

机构地区：[1]哈尔滨医科大学附属第四医院麻醉科,哈尔滨150001

出　　处：《医学综述》2015年第18期3285-3288,共4页Medical Recapitulate

基　　金：国家自然科学基金面上项目(81271456)

摘　　要：蛛网膜下腔出血(SAH)后心脏功能异常经常发生。实验研究和临床实践发现心肌肌钙蛋白I是检测SAH后心肌损伤的良好生物学指标。肌钙蛋白I在SAH患者中的变化,对预后的指导意义及病理生理学是目前研究热点。但是,肌钙蛋白I的临床作用存在争议,还需要大样本前瞻性的观察性研究来明确肌钙蛋白I对SAH患者预后的指导意义。Cardiac abnormalities frequently occur after subarachnoid hemorrhage（ SAH）. Experimental studies and clinical practices have found that cardiac troponin I（ c Tn I） is a good biological indicator for testing the cardiac injury after SAH. Currently,its variation,clinical significance and pathophysiology are the focus of studies. However its clinical function is still controversial,prospective,observational studies with sufficient sample size is still needed to assess whether c Tn I has a prognostic value for SAH.

关 键 词：蛛网膜下腔出血 心肌损伤 心肌肌钙蛋白Ⅰ 

分 类 号：R651.15[医药卫生—外科学]