基于关联规则对消化性溃疡方药组成规律的文献研究  

Composition Rule of Peptic Ulcer Prescriptions Based on Association Rules

作　　者：李强[1] 于文涛[2] 方朝义[1] 

机构地区：[1]河北中医学院针灸推拿学院,石家庄050200 [2]河北中医学院基础医学院,石家庄050200

出　　处：《中国实验方剂学杂志》2015年第19期201-203,共3页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家中医药管理局全国名老中医传承工作室建设项目(国中医药人教发[2011]41号);河北省中医药管理局科研计划项目(2011008);河北中医学院青年科研项目(QNZ2014033)

摘　　要：目的:探讨临床治疗消化性溃疡方药组成规律。方法:利用CNKI数据库检索到中医药治疗消化性溃疡文献99首,运用"中医传承辅助系统"对该文献方药组成进行数据挖掘分析,挖掘方法包括药物出现频次统计、药物组合关联规则分析。结果:99首方剂中共涉及中药147味,其中使用频次超过10次以上的药物共计29味;当支持度为20条件下,共得到药对40个;在置信度≥0.9的条件下,共得到药对8个。结论:健脾益气、疏肝理气、利湿化痰、清热泻火为临床治疗消化性溃疡最常用的药物,芍药甘草汤、乌及散、四逆散等传统方剂组合为治疗消化性溃疡常用配伍。Objective： To discuss the composition rule of clinical prescriptions for peptic ulcer. Method： Totally 99 Chinese medicine literatures for treating peptic ulcer were retrieved by CNKI database. Their clinical prescription composition data was mined by Traditional Chinese Medicine Inheritance Support System, the methods included drug frequency statistics and association rule analysis on drug combination. Result： Totally 29 herbs were used over 10 times in the 147 traditional Chinese medicine herbs in the 99 prescriptions; 40 medicine pairs were got in the condition of 20 support degree ; 8 medicine pairs were got when degree of confidence exceeded or equaled to 0.9. Conclusion： The most commonly used drugs for treating peptic ulcer in clinic were those strengthening the spleen and replenishing Qi, soothing the liver and regulating Qi, eliminating dampness and phlegm, and clearing fire medicines; peony licorice decoction, wujisan, and sinisan are common combined prescriptions for treating peptic ulcer.

关 键 词：消化性溃疡 数据挖掘 关联规则 中医传承辅助系统 

分 类 号：R287.1[医药卫生—中药学]