索茶碱联合噻托溴铵粉对COPD患者肺功能的改善作用  

Improvement effect of doxofylline combined with tiotropium bromide with COPD powder on pulmonary function in patients

作　　者：周敬奎[1] 

机构地区：[1]河南省漯河市中心医院呼吸内科,462000

出　　处：《中国实用医刊》2015年第20期14-15,共2页Chinese Journal of Practical Medicine

摘　　要：目的：研究索茶碱联合噻托溴铵粉对慢性阻塞性肺疾病（ COPD）患者肺功能的改善作用。方法选取COPD患者86例随机将其分为两组,对照组采用异丙托溴铵气雾剂治疗,观察组采用噻托溴铵粉药物护理疗法,对比两组患者的临床效果。结果观察组患者康复率为95．3%,住院时间为（8．59±1．36） d,生活质量评分为（89．31±3．29）分,明显高于对照组,两组比较差异有统计学意义（P〈0．05）。观察组患者的1秒用力呼气容积（FEV1）、用力肺活量（FVC）、FEV1/FVC等肺功能指标改善优于对照组（P〈0．05）,两组患者不良反应发生率比较差异未见统计学意义（P＆gt;0.05）。结论噻托溴铵粉对COPD患者肺功能具有较好的临床效果,疗程短,安全性高,患者较为满意,值得广泛推广。Objective To study the improvement effect of doxofylline combined with tiotropium bromide powder on pulmonary function in patients with COPD. Methods Eight-six patients with COPD were selected and they were randomly divided into two groups, the control group were treated with ipratropium bromide aerosol, and the observation group re-ceived tiotropium bromide powder nursing drug therapy, the clinical effects were compared between the two groups. Results In the observation group,the recovery rate was 95. 3%, the hospitalization time was （ 8. 59 ± 1. 36 ） d, the quality of life score was （89. 31 ±3. 29） points,compared with the control group, the differences were significant（P〈0. 05）. The im-provement of FEV1,FVC and FEV1/FVC in observation group were better than those in control group （P〈0. 05）. The in-cidence of adverse reactions had no significant difference between the two groups （ P＆gt;0. 05 ） . Conclusions Tiotropium bromide powder has better clinical effect on patients with pulmonary COPD, has short course of treatment, high safety, pa-tient satisfaction,it is worthy of extensive promotion.

关 键 词：索茶碱 噻托溴铵粉 慢性阻塞性肺疾病 

分 类 号：R511.6[医药卫生—内科学]