光动力法联合复方倍他米松注射在增生性瘢痕治疗中的应用  

Application of photodynamic therapy combined with compound betamethasone in treatment of hypertrophic scar

作　　者：方芳[1] 张虹[1] 赵雁[1] 林美玲[1] 

机构地区：[1]福建医科大学附属第一医院皮肤外科,福州350009

出　　处：《中华整形外科杂志》2015年第5期343-346,共4页Chinese Journal of Plastic Surgery

基　　金：福建省卫生厅青年基金（2013-2-45）

摘　　要：目的探讨光动力法联合复方倍他米松注射治疗增生性瘢痕的效果。方法37例患者随机分成2组，治疗组19例，对照组18例。治疗组采用光动力法联合复方倍他米松注射治疗，对照组单纯采用复方倍他米松局部注射治疗，比较治疗前、后的效果及复发率。结果治疗组有效率为89．5％，对照组55．6％，2组比较差异有统计学意义（P=0．029）；治疗组复发率5．9％，对照组40．0％，2组比较差异有统计学意义（P=0．047）。结论光动力法联合复方倍他米松注射治疗增生性瘢痕效果明显，能减少激素使用的时间及不良反应，安全性高，值得临床推广。Objective To investigate the effect of photodynamic therapy combined with compound betamethasone in the treatment of hypertrophic scar. Methods 37 cases of keloid were divided into two groups, 19 cases in the treatment group, 18 cases in the control group. The patients in treatment group were treated with photodynamic therapy combined with compound betamethasone injection therapy. The patients in the control group were treated by compound betamethasone injection. The effect and recurrence rate were compared before and after treatment. Results The effective rate was 89.5% in the treatment group, 55.6% in the control group, showing significant difference between the two groups （ P = 0. 029 ）. The relapse rate in treatment group was significantly lower than that in the control group （P = 0. 047）.Conclusions Photodynamic therapy combined with compound betamethasone has good effect and safety for the treatment of hypertrophic scar. The combined treatment can reduce the treatment period and side effects of hormone use.

关 键 词：光动力 复方倍他米松 增生性瘢痕 

分 类 号：R622[医药卫生—整形外科]