钨酸钠／过氧化氢体系对葡甲苷伯羟基的选择催化氧化  

Selective Oxidation of Primary Hydroxyl of Methyl Glucoside by Sodium Tungstate / Hydroperoxide

作　　者：张培[1] 袁华[1] 吴加雄[1] 张华良[1] 

机构地区：[1]武汉工程大学化学与环境工程学院,绿色化工过程教育部重点实验室,武汉430073

出　　处：《应用化学》2015年第10期1159-1163,共5页Chinese Journal of Applied Chemistry

基　　金：国家自然科学基金(21276201);武汉工程大学研究生教育创新基金项目(CX2014113)资助~~

摘　　要：采用钨酸钠/过氧化氢体系对甲基葡萄糖苷的伯羟基进行选择催化氧化制备葡萄糖醛酸及其内酯,考察了不同催化氧化工艺条件对反应收率的影响,产物用HPLC检测,同时对反应机理进行了初步探讨。结果表明,该体系对葡甲苷伯羟基的氧化具有较好的催化活性和反应选择性,葡萄糖醛酸及其内酯总收率可达到74.07%。与传统的淀粉硝酸氧化法工艺相比,该方法具有资源节约、环境友好的特点。Sodium tungstate/hydroperoxide was used for the preparation of glucuronic acid and its lactone by selective oxidation of primary hydroxyl group of methyl glucoside. The effects of different catalytic oxidative conditions on the yield were studied. The products were determined by HPLC. A reaction mechanism was proposed. The catalytic system exhibits high activity and good selectivity on the oxidation of primary hydroxyl of methyl glycoside. Combined yield of glucuronic acid and its lactone is up to 74. 07%. Compared with the traditional HNO3 oxidation of starch, this process is more environmental-friendly and economical.

关 键 词：钨酸钠/过氧化氢体系 葡甲苷 葡萄糖醛酸 选择氧化 

分 类 号：O643.3[理学—物理化学] TQ426[理学—化学]