使用自上而下法评估23项临床生化项目的测量不确定度  

Measurement uncertainty evaluation of 23 clinical biochemical items by top-down method

作　　者：刘辰庚[1] 张伟[1] 王培昌[1] 

机构地区：[1]首都医科大学宣武医院检验科,北京100053

出　　处：《医疗卫生装备》2015年第9期95-97,共3页Chinese Medical Equipment Journal

摘　　要：目的 :利用自上而下法对23项常用临床生化检测项目的不确定度进行评估。方法:针对日立7600全自动生化分析仪所测定的23项指标,利用室内质量控制和室间质量评价计算不确定度,再计算合成标准不确定度。结果:矫正前除Cl-、P、TCH和TG外,测量不确定度结果均可满足CLIA′88推荐可允许误差;矫正后除Cl-外所有结果均可满足CLIA′88推荐可允许误差。结论:通过自上而下法可对临床生化项目的不确定度有一定了解,但具体的测量不确定度评估合格标准还有待进一步探讨。Objective To evaluate the measurement uncertainty of 23 items of clinical biochemistry. Methods Internal quality control and external quality assessment were used to determine the uncertainty and standard uncertainty for the 23 items detected by Hitachi 7600 automatic biochemical analyzer. Results The uncertainties met the requirements of CLIA＇88 for allowable error before correction except those of Cl-, P, TCH and TG, and correction made those of P, TCH and TG satisfy the requirements. Conclusion The top-down method contributes to the understanding of the uncertainty of clinical biochemical items, while further efforts have to be performed for the uncertainty assessment standard.

关 键 词：测量不确定度 临床生化项目 自上而下法 

分 类 号：R446.1[医药卫生—诊断学]