淡色库蚊对吡丙醚的抗性选育及抗性风险评估  

Selection and risk assessment of resistance to pyriproxyfen in Culex pipiens pallens

作　　者：刘洪霞[1] 冷培恩[1] 徐劲秋[1] 刘曜[1] 

机构地区：[1]上海市疾病预防控制中心,上海200336

出　　处：《上海预防医学》2015年第9期533-536,共4页Shanghai Journal of Preventive Medicine

基　　金：上海市自然科学基金项目(12ZR1426600)

摘　　要：[目的]评估淡色库蚊对吡丙醚的抗性风险,预测抗性发展速率,为科学合理用药提供依据。[方法]采用群体汰选法获得抗性品系,采用数量遗传学的域性状分析法估算抗性现实遗传力(h2)并预测不同选择压下抗性发展速率。[结果]经过12代的室内选育,淡色库蚊对吡丙醚的抗性达到5.69倍,其对吡丙醚的h2为0.02,有一定抗性风险。[结论]淡色库蚊对吡丙醚有一定抗性风险,应科学合理用药。[ Objective ] To assess the resistance risk of Culex pipiens pallens to pyriproxyfen in Culexpipienz pallens, to predict the rate of resistance development and to provide the reference for scientific and rational application of insecticides. [ Methods ] The resistance strain was developed by group selection, and the realized heritability （ h^2 ） of Culex pipiens pallens resistance to deltamethrin was estimated by Tabashnik＇s method. [ Results ] The resistance of Culex pipiens pallens to pyriproxyfen had increased by 5.69 -fold after 12 generations of indoor breeding, and the h^2 of Culex pipiens paUens to pyriproxyfen was 0.02, indicating that a relatively risk of resistance development. [ Conclusion ] The results indicate that Culex pipiens pallens has resistance risk to pyriproxyfen, so the application of the insecticide must be scientific and rational.

关 键 词：淡色库蚊 吡丙醚 现实遗传力 抗性风险评估 

分 类 号：R184[医药卫生—流行病学]