尿微量清蛋白检测在老年动脉硬化中的临床价值  

Role of microalbuminuria in the elderly with atherosclerosis

作　　者：徐峰 

机构地区：[1]桂林市第二人民医院老年病科,广西桂林541000

出　　处：《国际检验医学杂志》2015年第19期2794-2795,共2页International Journal of Laboratory Medicine

基　　金：桂林市科学研究与技术开发计划基金资助项目(20110502)

摘　　要：目的对老年动脉硬化患者的动脉硬化指数(AASI)和尿微量清蛋白(MAU)的相关性进行探讨。方法根据是否存在MAU将89例老年动脉硬化患者分为2组,MAU阳性的患者为观察组,MAU阴性的患者为对照组,采用彩色超声对患者的颈动脉内膜厚度(IMT)进行测量,同时根据24h动态血压监测的数据结果计算AASI,对比分析2组的IMT和AASI,并进行相关分析和多元回归分析。结果观察组的IMT和AASI高于对照组,差异均有统计学意义(P<0.05)。相关分析显示AASI与MAU、IMT呈正相关;多元回归分析显示AASI与MAU呈正相关。结论 MAU检测对老年动脉硬化患者具有重要的临床价值。Objective To discuss the correlation of ambulatory arterial stiffness index （AASI） and microalbuminuria （MAU） in the elderly patients with atherosclerosis. Methods A total of 89 elderly patients with atherosclerosis were divided into two groups, patients with MAU positive as observation group, MAU negative patients as control group. To measure the intimal thickness （IMT） and calculate the AASI. Compared the IMT and AASI of two groups,and correlation analysis and multiple regression analy- sis were carried on. Results The IMT and AASI of observation group were higher than those of the control group,the differences between the two groups were statistical significant （P〈0.05）. The correlation analysis showed that AASI and MAU,IMT were positively correlated. Multiple regression analysis showed that AASI and MAU had positive correlation. Conclusion Microalbumin- uria has the vital significance in the elderly with atherosclerosis.

关 键 词：尿微量清蛋白 老年 动脉硬化 

分 类 号：R543.5[医药卫生—心血管疾病] R446.12[医药卫生—内科学]