北京某院2014年鲍曼不动杆菌的耐药性分析  

Drug resistance ananlysis of Acinetobacter baumannii strains isolated during 2014 in a hospital of Beijing

作　　者：邢献国[1] 杜新[1] 孟岩[1] 

机构地区：[1]首都医科大学丰台教学医院检验科,北京100070

出　　处：《国际检验医学杂志》2015年第19期2806-2807,共2页International Journal of Laboratory Medicine

摘　　要：目的了解该院2014年临床分离鲍曼不动杆菌对各类抗菌药物的耐药性,以指导临床合理用药。方法按常规方法进行细菌培养,对临床分离病原菌进行鉴定和药敏试验,使用Whonet5.6软件进行数据统计分析。结果该院2014年1~12月共分离到鲍曼不动杆菌226株,该菌对米诺环素、头孢哌酮/舒巴坦耐药率最低,分别为23.0%和30.1%,对其他抗菌药物的耐药率均高于50.0%。不同科室分离株对抗菌药物的耐药率不同,其中以ICU分离株耐药率最高。多重耐药和泛耐药鲍曼不动杆菌分别达到了71.2%、19.0%。结论鲍曼不动杆菌对多种抗菌药物耐药率高,应加强鲍曼不动杆菌耐药性监测,隔离泛耐药鲍曼不动杆菌感染者,防止医院内传播。Objective To investigate the drug resistance of Acinetobacter baumannii strains isolated during 2014 in a hospital of Beijing. Methods Isolated bacteria were cultured by routine method,identified and performed drug susceptibility test by bacteria a nalysis system. Statistical analysis of Acinetobacter baumannii was conducted by WhonetS. 6 software. Results A total of 226 Acin etobacter baumannii strains were isolated from January 2014 to December 2014 in Fengtai Teaching Hospital of Capital Medical U- niversity. These strains showed the lowest resistance rates to minocycline and Cefoperazone-sulbactam（23.0% and 30. 1 %）. The other antimicrobial resistance rates were more than 50.0 %. The resistance rate of Acinetobacter baumannii varied from one depart- ment to another. Pandrug-resistant and multi-drug resistant Acinetobacter baumannii were 71. 2%, 19. 0% respectively. Conclusion The resistant rates of Acinetobacter baumannii strains to a variety of antibiotics are high. It is essential to strengthen monitoring the drug resistance of Acinetobacter baumannii, as well as use antibiotics reasonable and separate patients to control Acinetobacter baumannii infection.

关 键 词：鲍曼不动杆菌 药敏试验 耐药性 

分 类 号：R446.5[医药卫生—诊断学]