Development of DNA computing and information processing based on DNA-strand displacement  

作　　者：Yafei Dong Chen Dong Fei Wan Jing Yang Cheng Zhang 

机构地区：[1]College of Life Science, Shaanxi Normal University [2]School of Control and Computer Engineering, North China Electric Power University [3]Key Laboratory of High Confidence Software Technologies of Ministry of Education [4]Software Engineering Institute [5]School of Electronics Engineering and Computer Science, Peking University

出　　处：《Science China Chemistry》2015年第10期1515-1523,共9页中国科学（化学英文版）

基　　金：supported by the National Natural Science Foundation of China(61272246,61370099,61272161,61127005,61133010,61425002,61320106005);the Graduate Education in Shaanxi Normal University Innovation Fund

摘　　要：DNA computing, currently a hot research field in information processing, has the advantages of parallelism, low energy consumption, and high storability, therefore, it has been applied to a variety of complicated computational problems. The emerging field of DNA nanotechnology has also developed quickly; within it, the method of DNA strand displacement has drawn great attention because it is self-induced, sensitive, accurate, and operationally simple. This article summarizes five aspects of the recent developments of DNA-strand displacement in DNA computing:(1) cascading circuits;(2) catalyzed reaction;(3) logic computation;(4) DNA computing on surfaces; and(5) logic computing based on nanoparticles guided by strand displacement. The applications and mechanisms of strand displacement in DNA computing are discussed and possible future developments are presented.DNA computing, currently a hot research field in information processing, has the advantages of parallelism, low energy consumption, and high storability, therefore, it has been applied to a variety of complicated computational problems. The emerging field of DNA nanotechnology has also developed quickly; within it, the method of DNA strand displacement has drawn great attention because it is self-induced, sensitive, accurate, and operationally simple. This article summarizes five aspects of the recent developments of DNA-strand displacement in DNA computing：（1） cascading circuits;（2） catalyzed reaction;（3） logic computation;（4） DNA computing on surfaces; and（5） logic computing based on nanoparticles guided by strand displacement. The applications and mechanisms of strand displacement in DNA computing are discussed and possible future developments are presented.

关 键 词：DNA computing information processing strand displacement SELF-ASSEMBLY NANOMATERIAL 

分 类 号：TP384[自动化与计算机技术—计算机系统结构]