不同剂量卡维地洛治疗冠心病合并2型糖尿病临床研究  

Clinical Study of Different Doses of Carvedilol in the Treatment of Coronary Heart Disease with Type 2 Diabetes Mellitus

作　　者：张全慧[1] 

机构地区：[1]资阳市第一人民医院心血管内科,四川资阳641300

出　　处：《糖尿病新世界》2015年第16期3-4,33,共3页Diabetes New World Magazine

摘　　要：目的探究并讨论使用剂量不同的卡维地洛冠心病合并2型糖尿病的治疗效果。方法 2014年5月—2015年5月间该院共接收的冠心病合并2型糖尿病患者共103例,分别接受低剂量和高剂量卡维地洛治疗的患者各为53例和50例,分成了对照组和治疗组两组,对不同剂量的治疗效果进行对比观察。结果治疗组和对照组治疗的总有效率分别为88.00%和62.26%,相比较下治疗组显著更高;治疗后治疗组患者空腹血糖及进食后2 h血糖血糖水平分别为(5.87±0.83)mmol/L、(8.41±1.29)mmol/L,明显低于对照组水平,差异有统计学意义(P<0.05)。结论高剂量的卡维地洛所取得的治疗效果更优,患者的血糖水平控制的更为理想。Objective To explore and discuss the effects of different doses of Carvedilol on coronary heart disease patients with type 2 diabetes mellitus. Methods A total of 103 patients with coronary heart disease and type 2 diabetes mellitus ad-mitted in our hospital from May 2014 to May 2015 were divided into the control group （53 cases） treated by low-dose Carvedilol and the treatment group （50 cases） treated by high-dose Carvedilol. And the treatment effect was compared be-tween the two groups. Results The treatment group had higher overall response rate than the control group （88.00% vs 62.26%）. After treatment, the fasting blood glucose level was （5.87±0.83） mmol/L, and 2-hour postprandial blood glucose level was （8.41 ±1.29） mmol/L in the treatment group, which was much lower than that in the control group, respectively, with statistically significant difference （P〈0.05）. Conclusion High-dose Carvedilol has better treatment effect, which can better control the blood sugar level of the patients.

关 键 词：2型糖尿病 冠心病 卡维地洛 

分 类 号：R587.1[医药卫生—内分泌]