双颌前徙手术治疗睡眠呼吸暂停综合征术后咽部气道形态学分析  

The morphological analysis of the pharyngeal airway after maxillomandibular advancement operation in the treatment of obstructive sleep apnea

作　　者：李宏峰 杨涛[2] 

机构地区：[1]解放军第461医院,吉林长春130000 [2]沈阳军区总医院口腔颌面外科,辽宁沈阳110016

出　　处：《中国医学工程》2015年第9期3-5,共3页China Medical Engineering

基　　金：辽宁省博士启动基金(20141179)

摘　　要：目的该研究通过对双颌前徙手术(MMA)治疗睡眠呼吸暂停综合征(OSA)患者和正常人的气道进行形态学观察分析,从而在气道形态上明确MMA手术治疗OSA的疗效。方法所有受试对象均进行术前咽部气道CT测量,其中OSA患者进行术后咽部气道CT测量。Student-t检验和线性回归统计学方法被应用于检测OSA患者术前、术后及正常人之间的头影测量关键点和气道的形态学改变。结果 24例患者(于2013年1月-2014年12月收治于沈阳军区总医院口腔颌面外科),其中12例患有OSA,余12例为对照组。笔者发现患者的术后气道容积、术后气道长度和术前、术后气道最小横截面存在统计学差异。经过MMA手术患者气道有明显的改善,其通气状况明显优于未手术患者。结论通过对比患者头影测量影像,MMA手术明显改善了OSA患者的通气情况,患者咽部气道形态上得到显著改善。[ Objective ] This study investigated the differences in airway morphology between control patients and those with obstructive sleep apnea （OSA） treated with maxillomandibular advancement （MMA） to gain better insight into the beneficial effects of MMA on airway morphology and OSA severity. [ Methods ] This case-control study included preoperative radiographic data gathered for all patients; postoperative radiographic data were gathered for the OSA group. Statistical analysis, including the Student t test, and simple linear regression was performed to identify differences in cephalometric and airway variables among the three groups and to associate airway morphology to disease severity. [ Results ] Twenty-four patients （12 with OSA; 12 controls） treated at the same clinic were included in this study. Statistically significant differences versus control values were found for preoperative total airway volume, postoperative airway length, and both pre- and postoperative airway minimum cross-sectional areas. The treated OSA airway showed significant morphologic improvements, comparable with the control group values. [ Conclusion ] MMA produces statistically significant airway improvements for OSA patients, producing airway morphology comparable with that of the controls.

关 键 词：双颌前徙手术 睡眠呼吸暂停综合征 气道 

分 类 号：R714.253[医药卫生—妇产科学]