16种中药颗粒剂对泛耐药鲍曼不动杆菌体外抑菌活性研究  

Study on the Extracorporal Antibacterial Activity of 16 Kinds of Chinese Herbal Medicine Granules on Pan Resistant Acinetobacter Bauman

作　　者：谭俊青[1] 李蔼文[1] 王康椿 黄双旺[1] 周兵[1] 刘启波[1] 

机构地区：[1]广东省第二中医院

出　　处：《按摩与康复医学》2015年第18期119-121,共3页Chinese Manipulation and Rehabilitation Medicine

基　　金：广东省中医药局课题项目,编号:20141020

摘　　要：目的：初步探讨黄连等16种中药颗粒剂对泛耐药鲍曼不动杆菌的体外抑菌效果.方法：采用肉汤稀释法测定黄连等16种中药颗粒剂悬液对ICU病区老年住院患者分离的10株泛耐药鲍曼不动杆菌的最低抑菌浓度（MIC）和最低杀菌浓度（MBC）.结果：金银花、穿心莲、败酱草、大青叶、连翘、黄岑、薄荷、艾叶、乌梅、秦皮、五味子、黄连等12种中药颗粒剂悬液具有不同程度的抑菌作用.结论：连翘、黄岑、薄荷、艾叶、乌梅、秦皮、五味子、黄连等8种中药颗粒剂悬液具有较好的抑菌作用,用于临床泛耐药鲍曼不动杆菌治疗具有一定的开发价值和应用前景。Objective：To investigate the extracorporal antibacterial effect of 16 kinds of Chinese herbal medicine granules on pan resistant acineto-bacter bauman. Methods：Minimum inhibitory concentration （MIC） and minimum bactericidal concentration （MBC） of 16 kinds of Chinese herbal medicine granules on 10 strains of Pan resistant Acinetobacter Bauman separated from aged inpatients in ICU were determined by broth dilution method. Results：Honeysuckle, common andrographis herb, herba patriniae, folium isatidis, fructus forsythiae, radix scutellariae, mint, artemsia ar-gyi, smoked plum, cortex fraxini, schisandra chinensis, rhizoma coptidis, the 12 kinds of Chinese herbal medicine granules suspension had different degrees of bacteriostatic action. Conclusion：Forsythia, scutellaria, mint, artemsia argyi, smoked plum, cortex fraxini, schisandra chinensis, rhizoma coptidis, the 8 kinds of Chinese herbal medicine granule suspension has good bacteriostatic effect, which in clinic treating pan drug resistant acineto-bacter baumannii has certain development value and application prospect.

关 键 词：中药颗粒剂 泛耐药鲍曼不动杆菌 体外抑菌实验 最低抑菌浓度(MIC) 最低杀菌浓度(MBC) 黄连 

分 类 号：R446.5[医药卫生—诊断学]