糖耐量异常患者的中医证型与胰岛β细胞功能的相关性研究  

Correlation between TCM Syndrome Type and Islet Beta Cell Function in Patients with Impaired Glucose Tolerance

作　　者：孙睦[1] 

机构地区：[1]中国中医科学院眼科医院综合内科,北京100040

出　　处：《中国医药导刊》2015年第9期914-915,共2页Chinese Journal of Medicinal Guide

摘　　要：目的:探讨糖耐量异常(IGT)患者的中医证型与相关检查、实验室指标的相关性。方法:随机收集眼科医院的糖耐量异常患者72例,判定中医证候,并测定体重指数(BMI)、血糖、胰岛素水平、胰岛素抵抗指数(HOMA-IR)、胰岛β细胞素分泌指数(HOMA-β),研究他们之间的相关性。结果:气虚痰湿组、阴虚燥热组、气阴两虚组BMI均显著增高;气阴两虚组血糖水平最高;气虚痰湿组胰岛素水平最高;各证型间HOMR-IR表现为逐渐增高,阴虚燥热证<气虚痰湿<气阴两虚证;各证型间HOMA-β逐渐降低,阴虚燥热证>气虚痰湿>气阴两虚。结论:IGT的中医证型与BMI、血糖、胰岛素水平及胰岛β细胞功能有一定的相关性,可以作为临床中医辩证参考。Objective： To investigate the correlation between TCM syndromes and related examinations and laboratory indexes in patients with impaired glucose tolerance （IGT）.Methods：72 patients with abnormal glucose tolerance were randomly collected from the department of ophthalmology, and the TCM syndromes were determined, and their body mass index （BMI）, blood glucose, insulin level, insulin resistance（HOMA-tR）, index beta cell secretion index （HOMA-） were measured.ResulCs： Qi deficiency and phlegm wet group, yinxuzaore group,deficiency of both qi and Yin group BMI were significantly increased; deficiency of both qi and Yin group, the levels of blood glucose level highest;Qi deficiency and phlegm dampness group, insulin level was the highest.Each card type HOMA-IR for increased gradually,dryness heat due to deficiency of Yin Syndrome〈Qi deficiency and phlegm dampness-〈gas Yin deficiency syndrome; the syndrome between HOMA beta decreased gradually, dryness heat due to deficiency of Yin Syndrome〉Qi deficiency and phlegm dampness〉deficiency of both qi and Yin.Conclusion：TCM syndrome types of IGT are related to BMI, blood glucose, insulin and pancreatic islet beta cell function,which can be used as a reference for clinical medicine.

关 键 词：糖耐量异常 中医证候 检查指标 相关性分析 

分 类 号：R259[医药卫生—中西医结合] R587.1[医药卫生—中医内科学]