左卡尼汀联合促红细胞生成素对维持性血液透析患者贫血和微炎症状态的影响  

The Impact of L-carnitine Combined With EPO on Maintenance Hemodialytic Patients With Anemia and Microinflammatory

作　　者：胡泳[1] 

机构地区：[1]南京中医药大学附属中西医结合医院,210000

出　　处：《中国继续医学教育》2015年第26期133-134,共2页China Continuing Medical Education

摘　　要：目的观察左卡尼汀联合促红细胞生成素(EPO)对维持性血液透析患者贫血和微炎症的影响。方法 50例慢性肾衰竭维持性血液透析患者随机分为治疗组和对照组,对照组单独给予皮下注射EPO治疗,治疗组在EPO的基础上静脉注射左卡尼汀。观察两组患者治疗前后RBC、Hb、Hct以及CRP和血白蛋白的变化。结果两组患者治疗后RBC、Hb以及Hct水平比治疗前均升高,且治疗组患者RBC、Hb以及Hct的升高水平高于对照组;治疗组血清CRP的水平均较治疗前下降,血白蛋白水平升高,而对照组治疗前后血清CRP以及血白蛋白水平均未发生明显改变。结论左卡尼汀联合EP0能改善维持性血液透析患者的贫血以及微炎症状态。Objective To observer the effect of L-carnitine combined with EPO on maintenance hemodialytic patients with anemia and microinlfammatory.MethodsSelected 50 cases of Renal Failure patients （CFP） on maintenance hemodialytic were divided into treatment group and control group randomly, the control group were given EPO intravenously alone, the treatment group were treated additionally with L-carnitine by intravenous injection. To observe the changes of RBC, Hb and Hct, also CRP and serum albumin before and after the different treatment.Results The levels of RBC, Hb and Hct increased in both groups than that before treatment, and the treatment group improved more signiifcantly the level of CRP decreased and the level of serum albumin increased after treatment in treatment group, but the levels of the two were no signiifcant difference in control group.Conclusion The combined treatment of L-carnitine and EPO can significantly improve the anemia and microinflammatory in maintenance hemodialytic patients.

关 键 词：左卡尼汀 促红细胞生成素 慢性肾衰竭 贫血 微炎症 

分 类 号：R692.5[医药卫生—泌尿科学]