舌下含服粉尘螨滴剂治疗儿童变应性鼻炎合并腺样体肥大的临床观察  

Clinical observation of sublingual dermatophagoides farinae treatment of allergic rhinitis with adenoid hypertrophy in children

作　　者：谢小娟[1] 文春秀[1] 甘金梅[1] 蒋鸣惊[1] 莫誉华[1] 黄跃[1] 

机构地区：[1]广西壮族自治区妇幼保健院耳鼻咽喉科,530000

出　　处：《中国保健营养》2015年第7期10-11,共2页China Health Care & Nutrition

基　　金：广西壮族自治区卫生厅自筹经费科研课题（Z2013261）.

摘　　要：目的：探讨舌下含服粉尘螨滴剂对儿童变应性鼻炎合并腺样体肥大的临床治疗效果.方法：将64例变应性鼻炎合并腺样体肥大患儿随机分为两组，研究组为舌下含服粉尘螨滴剂治疗，对照组为单纯常规抗过敏药物治疗，观察2年，采用 VAS 评分记录患儿临床症状的变化，采用鼻内镜检查观察腺样体大小的改变.结果：研究组鼻过敏症状VAS 评分较治疗前显著下降（P ＜0．05），治疗后两组之间鼻过敏症状 VAS 评分有显著差异（P ＜0．05）；治疗后研究组打鼾等症状 VAS 评分显著低于治疗前（P ＜0．05），且打鼾等症状 VAS 评分较对照组有显著降低（P ＜0．05）；治疗2年后两组腺样体大小较治疗前减小有统计学差异（P ＜0．05），两组间的比较有显著差异（P ＜0．05）.结论：舌下含服粉尘螨滴剂可有效控制儿童变应性鼻炎合并腺样体肥大的鼻塞、鼻痒、打喷嚏、流涕、睡眠打鼾症状及腺样体大小，可作为非手术治疗变应性鼻炎合并腺样体肥大的临床方法.Objective：To investigate the clinical effect of sublingual dermatophagoides farinae drops on allergic rhinitis with adenoid hypertrophy in children.Methods：Diagnosis for allergic rhinitis with adenoid hypertrophy of 64 cases were randomly divided into two groups,study group under the tongue with dermatophagoides farinae drops in treatment and control group for the simple routine anti allergy drug treatment were observed for 2 years,changes in VAS scores were recorded at children with nasal allergies such as nasal congestion,nasal itching,sneezing and runny nose and sleep snoring symptoms,by nasal endoscopy to observe the changes of the size of adenoids.Results：The VAS score of nasal allergic symptoms in the study group was significantly decreased （P 〈0.05）compared with that before treatment.There was significant difference in the VAS score between the two groups after treatment （P〈0.05）.After treatment,the symptoms such as snoring in the study group were signifiG cantly lower than those in the treatment group （P 〈0.05）,and the symptoms such as snoring and VAS scores were significantly lower than those in the control group （P〈0.05）;and the two groups of adenoid body size compared with the treatment before the reduction of the difference between the two groups （P〈0.05）,the comparison between the groups were significantly different （P〈0.05）.ConcluG sion：The tongue with dermatophagoides farinae drops can effectively control children with allergic rhiG nitis with adenoid hypertrophy of the stuffy nose,nasal itching,sneezing,runny nose,sleep snoring and adenoid body size,as the non operative treatment of allergic rhinitis with adenoid hypertrophy clinical method.

关 键 词：儿童 鼻炎 变应性 腺样体肥大 免疫治疗 粉尘螨滴剂 

分 类 号：R45[医药卫生—治疗学]