玻璃化冻融胚胎移植结局的相关因素分析  

Analysis of influence factors of the outcomes of the vitrified frozen-thawed embryo transfer

作　　者：李荣[1] 丘映[1] 谭秀群[1] 黄颖[1] 唐稚莉[1] 江莉[1] 

机构地区：[1]南宁市第二人民医院生殖医疗中心,广西南宁530031

出　　处：《中国计划生育和妇产科》2015年第10期31-34,共4页Chinese Journal of Family Planning & Gynecotokology

基　　金：广西卫生厅科研课题(项目编号:Z2014456)

摘　　要：目的探讨与玻璃化冻融胚胎移植结局相关的影响因素。方法对广西南宁市第二人民医院生殖医学中心接受玻璃化冷冻胚胎移植的患者共237个周期的相关资料进行回顾性分析,根据患者年龄、不孕年限、受精方式、内膜准备方式、移植胚胎质量进行分组,比较各组的临床妊娠率,采用logistic回归模型分析影响临床妊娠率的相关因素。结果不同年龄、不孕年限、移植胚胎质量对临床妊娠率的影响有统计学意义(P<0.05),而不同受精方式、不同内膜准备方案的临床妊娠率差异无统计学意义(P>0.05)。logistic回归分析显示年龄和移植胚胎质量是影响临床妊娠结局的主要相关因素。结论在玻璃化冻融胚胎移植周期中,年龄、移植胚胎质量是妊娠成功的重要影响因素。Objective To explore the influence factors of the outcomes of the vitrified frozen - thawed embryo transfer. Methods Clinical data of 237 circles of vitrified frozen - thawed embryo transfer in The Second Affiliated Hospital of Guangxi Medical University were retrospectively analyzed. All cases were divided into several groups according to the patients＇ age, time of infertihty, methods of fertilization, endometrial preparation methods and quality of embryo, and the clinical pregnancy rate were compared. Logistic regression was used to analyze the influencing factors of clinical pregnancy rate. Results There were significant differences between different patients＇ age, time of infertility, and quality of transfer embryo in regard to clinical pregnancy rate. No significant differences were found among the methods of fertilization, and endometrial preparation methods （ P 〉 0.05 ）. Logistic regression revealed that patients＇ age and quality of transfer embryo were main influencing factors of the clinical pregnancy rate. Conchmion The patients＇ age and quality of transfer embryo the are important factors influencing the success of frozen - thawed embryo transfer.

关 键 词：玻璃化 冻融胚胎移植 临床妊娠率 相关因素 

分 类 号：R711.6[医药卫生—妇产科学]