中医序贯疗法治疗急性鼻-鼻窦炎的临床研究  

Clinical study on the TCM sequential therapy in the treatment of acute rhinosinusitis

作　　者：李美静[1] 刘娇媚[2] 刘昱辛 杨丽[1] 荣堃[1] 雷剑波[1] 乔锦[1] 常远[1] 左立镇 张予[1] 孙书臣[1] 

机构地区：[1]中国中医科学院广安门医院耳鼻喉科,北京100053 [2]中国中医科学院广安门医院南区耳鼻喉科,北京102600

出　　处：《国际中医中药杂志》2015年第10期890-893,共4页International Journal of Traditional Chinese Medicine

基　　金：北京市科学技术委员会首都市民健康项目培育（Z131100004013015）

摘　　要：目的 观察中医序贯疗法治疗急性鼻-鼻窦炎的临床疗效.方法 108例肺经风热型急性鼻-鼻窦炎、慢性鼻-鼻窦炎急性发作患者按照随机数字表法随机分为3组各36例,序贯疗法组采用煎药蒸气熏蒸鼻窍并口服治疗,连续用药1周,再单纯用煎药蒸气熏蒸鼻窍,连续1周;口服汤药组：采用与序贯疗法组相同的煎药口服2周;口服西药组：口服阿莫西林克拉维酸钾片,连续服用2周.分别于治疗前后观察并记录各组患者的鼻塞、流涕、鼻黏膜充血肿胀程度、头痛、嗅觉障碍、局部压痛的积分及病情程度视觉模拟量表、鼻塞视觉模拟量表积分.结果 序贯疗法组、口服汤药组、口服西药组的总有效率分别为91.7%、84.4%、86.2%,差异无统计学意义（P〉0.05）.2组的痊愈、显效、有效、无效的疗效等级比较差异有统计学意义（χ^2=10.660,P=0.010）.治疗第 14 天,鼻塞积分、鼻黏膜充血肿胀程度积分、鼻塞视觉模拟量表积分、总积分,序贯疗法组[分别为（0.39±0.80）分、（1.44±1.83）分、（0.62±1.55）分、（3.94±3.26）分],与口服汤药组[分别为（0.94±1.24）分、（2.44±2.02）分、（1.28±1.44）分、（6.94±5.54）分]、口服西药组[分别为（1.10±1.15）分、（3.24±1.96）分、（1.59±2.15）分、（7.10±4.06）分]比较,差异有统计学意义（P〈0.05）.结论 中医序贯疗法治疗急性鼻-鼻窦炎、、慢性鼻-鼻窦炎急性发作疗效显著,且安全无明显不良反应。Objective To assess the clinical eficacy of TCM sequential therapy treatment of acute rhinosinusitis.Methods 108 acute rhinosinusitis of the Lung Channel with wind-heat type patients were divided into three groups according to random digits table： sequential therapy group, traditional Chinese medicine group, and western medicine group. On day 0, day 7, day 14, recorded the date of nasal obstruction, running nose, nasal mucosa congestion degree of swelling, headache, smell disorders, local tenderness points , the severity of the disease visual analogue scale, nasal obstruction visual analogue scale. We regarded 2 weeks as a course of treatment.Results The total efficiency was 91.67% in the sequential therapy group, 84.37% in the traditional Chinese medicine, 86.21% in the western medicine group, with no significant difference （P〉0.05）. There was a significant difference in efficacy level of the total recovery, obvious efficiency, efficiency and no efficiency （P〈0.05）. In the date of nasal obstruction, nasal mucosa congestion degree of swelling, nasal＆amp;nbsp; obstruction visual analogue scale and the total score, the sequential therapy group （0.39±0.80）, （1.44±1.83）, （0.62±1.55）,（3.94±3.26）respectively, was significantly improved than the Chinese medicine group （0.94± 1.24）, （2.44±2.02）, （1.28±1.44）, （6.94±5.54）respectively, and the western medicine group （1.10±1.15）, （3.24±1.96）, （1.59±2.15）,（7.10±4.06） respectively on 14 day（P〈0.05）.Conclusion The curative effect of sequential therapy of traditional Chinese medicine in the treatment of acute rhinosinusitis is distinct and safe.

关 键 词：苍耳子散 急性鼻-鼻窦炎 中医序贯疗法 

分 类 号：R765.4[医药卫生—耳鼻咽喉科]