颈动脉粥样硬化与冠状动脉SYNTAX积分的相关性研究  

The correlation between SYNTAX integral of coronary artery and carotid artery atherosclerosis

作　　者：彭松[1] 万静[1] 李凯勇[1] 方冬[1] 方奇[1] 

机构地区：[1]武汉大学中南医院心内科,430071

出　　处：《心肺血管病杂志》2015年第8期602-605,610,共5页Journal of Cardiovascular and Pulmonary Diseases

摘　　要：目的:研究颈动脉粥样斑块病变情况与冠状动脉SYNTAX积分的关系,探讨颈动脉粥样硬化(As)的病变程度,对冠心病患者的冠状动脉病变程度及其预后的预测作用。方法:选取武汉大学中南医院心内科,2012年1月至2013年9月,住院行冠状动脉造影患者296例,根据结果进行SYNTAX评分,并分为轻度组(1<积分<21)51例,中度组(21<积分<31)71例,重度组(积分>31)136例,以及对照组(0分)38例,采用颈动脉超声检查患者的颈动脉As病变情况,并采用AS评分及Crouse评分对颈动脉As病变情况进行量化。结果:随着冠状动脉病变情况的加重,颈动脉粥样斑块的发生率明显增高,且病变程度也逐渐加重;针对冠状动脉病变情况的SYNTAX评分和针对颈动脉病变情况的AS评分之间的相关系数r=0.865(P<0.01),其对冠心病预测作用的曲线下面积AUC=0.9(P<0.01),与Crouse评分之间的相关系数r=0.852(P<0.01),曲线下面积AUC=0.89(P<0.01)。结论:颈动脉As与冠状动脉病变严重情况相关,颈动脉超声是筛查冠心病的有力手段。Objective： Objective：To study the relationship between carotid atherosclerosis plaque lesions and SYNTAX integral of coronary artery stenosis and to explore the connection and prognosis prediction of the degree of carotid atherosclerotic and coronary artery stenosis in patients with coronary heart disease. Methods： Totally choosing 296 cases from the patients who were in the cardiology department of Zhongnan hospital from Junuary 2012 to September 2013, using SYNTAX score to grade them according to the results of coronary angiography, and basing on the results it can be divided into three groups, such as mild coronary artery lesions group （ 〈 21 score） 51 cases, moderate group （21 -31 score） 71 cases, severe group （ 〉31 score） 136 cases, and the control group 38 cases, all of them are examined the atherosclerotic lesions by Echocardiography, and use spssl7. 0 software for statistical analysis. Results： With the progress of coronary artery lesions, the incidence and lesion of carotid atherosclerotic plaque are significantly higher; On the other hand, the coefficient between the SYNTAX score about coronary artery disease and the AS scores is 0. 865 （P 〈 0. 01 ） , the area under the curve is 0. 9 （P 〈 0. 01 ） , and the Crouse score is 0. 852 （P 〈 0. 01 ） and 0. 89 （P 〈 0. 01 ）. Conclusion： Carotid atherosclerosis lesions has something to do with the severity of coronary artery disease, thus it can be used to screen for the patients with coronary heart disease at early time.

关 键 词：颈动脉粥样硬化 冠状动脉造影术 SYNTAX积分 AS积分 Crouse积分 

分 类 号：R54[医药卫生—心血管疾病]