正天丸(胶囊)气相色谱研究  

Studies on GC Analysis of Zhengtian Pills and Zhengtian Capsules

作　　者：陈惠玲[1,2] 胡睿恩[1,2] 黄澜[1,2] 李玲玲[1,2] 

机构地区：[1]厦门市药品检验所 [2]厦门大学药学院,厦门361000

出　　处：《海峡药学》2015年第9期52-54,共3页Strait Pharmaceutical Journal

摘　　要：目的建立正天丸(胶囊)的气相色谱指纹图谱,进行药品的评价和控制。方法采用水蒸气蒸馏法提取正天丸(胶囊)中的挥发性成分,并通过气相色谱法进行分析,建立了气相色谱指纹图谱。利用中药指纹图谱相似度计算软件(2009版)进行分析和评价。结果 54批正天丸和5批正天胶囊的相似度均大于0.9,并分别确立了正天丸的18个共有峰及正天胶囊的13个共有峰。结论通过建立指纹图谱模式,为正天丸(胶囊)提供一种质量评价方法和检测模式。OBJECTIVE To constitute the finger print of Zhengtian Pills and Zhengtian Capsules ,hence to provide reference for the evaluation and the control.METHODS The volatile components in Zhengtian Pills and Zhengtian Capsulaes were extracted by hydrodistillation and detected by gas chromatography （ GC ）.GC fingerprints were established ,analyzed and evaluated according to the evaluation system of the similarity of the finger prints of Chinese medicines （2009 ）.RESULTS 54 batches of Zhengtian Pills and 5 batches of Zhengtian Capsules had high similarity fingerprints.18 apexes had been screened in Zhengtian Pills fingerprints and 13 apexes had been screened in Zhengtian Capsulaes fingerprints.CONCLUSION The common pattern of the fingerprint chromatogram as established,which provide a quality standard and testing method for Zhengtian Pills and Zhengtian Capsules .

关 键 词：正天丸(胶囊) 气相色谱 指纹图谱 挥发油成分 

分 类 号：R917[医药卫生—药物分析学]