我院微生物检查常见检出菌及耐药性分析  

Analysis of Common Pathogens of Microorganism Examination and Drug Resistance in Our Hospital

作　　者：陈奕伸[1] 杨盈盈[1] 梁嘉碧[1] 洪仲思[1] 

机构地区：[1]中山大学附属第五医院,广东珠海519000

出　　处：《中国药房》2015年第29期4072-4076,共5页China Pharmacy

摘　　要：目的:了解我院临床上常见检出菌株的分布及耐药情况,为临床经验治疗提供参考,指导临床合理使用抗菌药物。方法:收集2010年8月-2014年9月我院临床送检的微生物培养、分离、鉴定及药敏试验结果,将分离出的细菌及药敏资料进行统计、分析。结果:4年间共分离或培养出各种病原体14 687株,其中革兰阴性菌以铜绿假单胞菌1 790株居首,其次为大肠埃希菌1 313株,肺炎克雷伯菌肺炎亚种770株,鲍曼不动杆菌670株;革兰阳性菌以金黄色葡萄球菌915株居首,其次为粪肠球菌223株,溶血葡萄球菌98株;其他微生物检出最多的是解脲支原体1 446株,白假丝酵母菌769株,人型支原体187株。结论:定期的检出菌分布调查及细菌耐药性监测有利于了解医疗机构内部的细菌耐药性变化,为临床经验用药提供指导,促进抗菌药物合理应用。OBJECTIVE：To investigate the distribution of common bacterial pathogens and their drug resistance in our hospital,and to provide guidance for clinical treatment and promote rational drug use. METHODS：The results of microorganism culture,isolation and identification,and drug sensitivity test were collected from our hospital during Aug. 2010-Sept. 2014. The isolated pathogens and drug sensitivity were analyzed statistically. RESULTS：14 687 strains of bacterial pathogens were isolated or cultured in 4 years,among which 1 790 strains of Pseudomonas aeruginosas were most common Gram-negative bacterium,followed by 1 313 strains of Escherichia coli and 770 strains of Klebsiella pneumoniae,670 strains of Bauman acinetobacter;915 strains of Staphylococcus aureus were most common Gram-positive bacterium,followed by 223 strains of Enterococcus faecalis,98 strains of Staphylococcus haemolyticus;1 446 strains of Mycoplasma urealytium were the most common microorganism,followed by 769 strains of Candida albicans,187 strain of Mycoplasma hominis. CONCLUSIONS：Regular detection of bacteria distribution and bacterial resistance monitoring are conducive to understand the bacterial resistance of the medical institutions so as to provide guidance for clinical treatment and promote reasonable application of antibacterial drugs.

关 键 词：微生物检查 检出菌 抗菌药物 敏感性 合理用药 

分 类 号：R969.1[医药卫生—药理学] R978.1[医药卫生—药学]