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机构地区:[1]河南大学第一附属医院,河南开封475001 [2]河南大学中药研究所,河南开封475004
出 处:《中国药房》2015年第29期4099-4101,共3页China Pharmacy
基 金:河南省高等学校重点科研项目(No.15A350002)
摘 要:目的:观察健骨痛消丸治疗骨关节炎的临床疗效。方法:将骨关节炎患者72例按随机数字表法分为治疗组和对照组,各36例。治疗组患者口服健骨痛消丸,每次5 g,每日3次;对照组患者口服硫酸氨基葡萄糖胶囊,每次0.5 g,每日3次。均以7 d为1个疗程,两组共治疗4个疗程。观察并比较两组患者的临床疗效、Mc Master大学骨关节炎指数(WOMAC)评分和视觉模拟评分法(VAS)评分。结果:治疗后,治疗组患者总有效率(94.44%)明显优于对照组(83.33%),差异有统计学意义(P<0.05);治疗组患者WOMAC积分和VAS评分均低于对照组,差异有统计学意义(P<0.05)。结论:健骨痛消丸治疗骨关节炎疗效较好。OBJECTIVE:To observe therapeutic efficacy of Jiangu tongxiao pills in the treatment of osteoarthritis. METHODS:72 patients with osteoarthritis were randomly divided into treatment group and control group with 36 cases in each group.Treatment group was given Jiangu tongxiao pill orally,5 g/time,3 times/d;control group was treated with Glucosamine sulfate capsules orally. 0.5 g/time,3 times/d. A treatment course lasted for 7 days,and both group received 4 treatment courses. Clinical efficacy,WOMAC score and VAS score were observed and compared between 2 groups. RESULTS:The total effective rate of treatment group(94.44%)was obviously superior to that(83.33%)of control group,with statistical significance(P〈0.05). WOMAC score and VAS score of treatment group were lower than those of control group,with statistical significance(P〈0.05). CONCLUSIONS:Jiangu tongxiao pills has good therapeutic efficacy for osteoarthritis.
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